| Project/Area Number |
26440177
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Animal physiology/Animal behavior
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| Research Institution | Miyagi University of Education |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
TACHIBANA KAZUNORI 東京工業大学, バイオ研究基盤支援総合センター, 准教授 (60212031)
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| Research Collaborator |
ARAKAWA MIO
ENDO KAZUKI
SUGAWARA AKARI
TAKAHASHI RYO
TAKEDA NORIYO
HOSHI TAKAHITO
YAMAKAWA NAHOMI
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 卵母細胞 / 生殖巣 / エダアシクラゲ / 神経ペプチド / 卵成熟 / 卵核胞崩壊 / 卵巣上皮 |
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| Outline of Final Research Achievements |
Jellyfish oocytes undergo meiotic maturation in the ovary following a dark-light or light-dark transition (light or dark stimulation) and are then released as mature eggs. The present study provides evidence that a C-terminal amidated tetrapeptide, RPRPa, exists in neural-type cells in the ovarian epithelium and acts as maturation-inducing hormone (MIH) downstream of dark stimulation in Cladonema pacificum. Our data also indicate that slightly different neuropeptides may function in other jellyfish species. Furthermore, we confirm here that these neuropeptides can induce the release of sperm as well as eggs. To our knowledge, this is the first identification of peptidic MIHs among all animals.
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