| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
Compensatory molecular evolution refers to the process where the fixation of multiple mutation that are singly deleterious maintain organismal fitness by compensating their effects. In this research project, we mainly focus on the compensatory weak selection model, where the fixation of slightly advantageous mutations follow the fixation of slightly deleterious mutations in a variety of molecular systems, including protein-protein interaction and gene expression.
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