Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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Outline of Final Research Achievements |
We found that TAS1, the tenuazonic acid biosynthetic gene of the rice blast fungus, codes for a new-type secondary metabolite biosynthetic enzyme, and involved in infection. We also found that environmental signals induce tenuazonic acid production via an epigenetic regulator and a transcription factor. Furthermore, we isolated a tenuazonic acid production-inducing compound from a chemical library. This compound induced production of secondary metabolites in other fungus, suggesting that there is a common mechanism in secondary metabolite production control.
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