| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
In the developing endosperm cells of rice (Oryza sativa), disulphide bonds enable redox control of protein packaging into the protein storage organelles, thus providing nutritional reserves for the next generation. In this study, we aimed at unravelling the mechanisms that modulate the redox pathways for disulphide bond formation, which generate hydrogen peroxide as a by-product. The pathways for disulphide bond formation require de novo disulphide-generating enzyme (e.g. ERO1) and disulphide carrier protein (e.g. PDI) in the endosperm cells of rice. A potential function of the QSOX family member, which catalyses both de novo disulphide generation and disulphide transfer, is discussed.
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