| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Outline of Final Research Achievements |
It has been reported that some of depression symptom shows decreased serum zinc concentration, serotonin secretion. In order to investigate the effects of marginal zinc deficiency on psychological development and mood disorder in growing rats, we monitored the locomotive activity and secretion of norepinephrine and serotonin from brain. We found that locomotive activity of zinc-deficient rats during the dark period significantly decrease after 12 days of feeding. It suggests that decreased locomotive activity might be associated with depression symptom. On day 4, secretion of norepinephrine and serotonin from lateral hypothalamus of zinc-deficient rats decreased compared with control rats.
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