Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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Outline of Final Research Achievements |
In this study, we examined how the sphingolipids, polyphenols, or polysaccharide in food affect the function of plasma membrane on enteroendocrine cells, We focused on the receptor of long-chain fatty acid, GPR120, and developed a new method to assay fatty acid/ GPR120 signaling employing TGF alpha- shedding assay. The method was convenient and showed high quantity. Using this method, we found several new ligand and molecules which affect alpha linolenic acid/ GPR120 signaling.
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