Induction of brown-like adipocytes in white adipose tissue by food-derived factors
Project/Area Number |
26450168
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Food science
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Research Institution | Chubu University |
Principal Investigator |
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Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 食品由来因子 / 肥満 |
Outline of Final Research Achievements |
Induction of brown-like adipocytes in white adipose tissue suggests a new approach for preventing and treating obesity via induction of thermogenesis aasociated with uncoupling protein 1. Here, we demonstrate that several food-derived factors significantly induces brown-like adipocytes in cells and mice. These findings may provide insight into browning of white adipocytes including the molecular mechanism mediated by food-derived factors and demonstrate that food-derived factors have a novel biological function with regard to increasing energy expenditure by browning of white adipocytes.
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Report
(4 results)
Research Products
(42 results)
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[Journal Article] Curcumin improves glucose tolerance via stimulation of glucagon-like peptide-1 secretion.2017
Author(s)
Kato, M., Nishikawa, S., Ikehata, A., Dochi, K., Tani, T., Takahashi, T., Imaizumi, A., Tsuda, T.
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Journal Title
Mol. Nutr. Food Res.
Volume: 61
Issue: 3
Pages: 1600471-1600471
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Artepillin C, a typical Brazilian propolis-derived component, induces brown-like adipocyte formation in C3H10T1/2 cells, primary inguinal white adipose tissue-derived adipocytes, and mice.2016
Author(s)
Nishikawa, S., Aoyama, H., Kamiya, M., Higuchi, J., Kato, A., Soga, M., Kawai, T., Yoshimura, K., Kumazawa, S., Tsuda, T.
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Journal Title
PLoS ONE
Volume: 11
Issue: 9
Pages: e0162512-e0162512
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Dietary sweet potato (Ipomoea batatas L.) leaf extract attenuates hyperglycaemia by enhancing the secretion of glucagon-like peptide-1 (GLP-1).2014
Author(s)
Nagamine, R., Ueno, S., Tsubata, M., Yamaguchi, K., Takagaki, K., Hira, T., Hara, H., Tsuda, T.
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Journal Title
Food & Function
Volume: 5
Issue: 9
Pages: 2309-2316
DOI
Related Report
Peer Reviewed
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[Presentation] Sweet potato (Ipomoea batatas L.) leaf extract increases glucagon-like peptide-1 (GLP-1) release and attenuates hyperglycemia in rodent models.2014
Author(s)
Nagamine, R., Ueno, S., Tsubata, M., Yamaguchi, K., Takagaki, K., Hira, T., Hara, H., Tsuda, T.
Organizer
27th International Conference on Polyphenols
Place of Presentation
Nagoya University, Nagoya, Aichi
Year and Date
2014-09-02 – 2014-09-06
Related Report
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[Presentation] クルクミンと消化管ホルモン分泌2014
Author(s)
津田孝範
Organizer
第14回日本抗加齢医学会総会シンポジウム
Place of Presentation
大阪国際会議場(大阪府・大阪市)
Year and Date
2014-06-06 – 2014-06-08
Related Report
Invited
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[Book] 食品学2014
Author(s)
津田孝範
Total Pages
166
Publisher
朝倉書店
Related Report