| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
A large amount of economic loss in poultry industry is produced by specific disorders such as the leg weakness and eggshell broken. The disorders are closely related with bone metabolism. Bone is composed of hydroxyapatite (phosphorus and calcium). Therefore, phosphorus metabolism also plays an important role in bone health.
In this research project, the mRNAs of sodium-dependent phosphate transporter (NaPi-II) were expressed in intestines and kidney, and the NaPi-II mRNAs were increased with the growth and maturation of female chickens. The NaPi-II mRNA expression was also stimulated by 1,25-hydroxyvitamin D3 (1,25-OH2D3) and estrogen. These results demonstrated that phosphorus metabolism during sexual maturation is regulated by the estrogen-induced 1,25-OH2D3 production.
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