| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
We studied the role of MARCKS protein in endothelial cells, smooth muscle cells, and platelets. In endothelial cells, MARCKS protein was involved in cell proliferation, cell migration, and nitric oxide production. Furthermore, participation of MARCKS in abnormal cell functions of diabetes or methylmercury intoxication model animals was suggested. In addition, MARCKS was expressed in smooth muscle cells and platelets, and the role of MARCKS in these cells was indicated.
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