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Mechanism of reproductive physiology under the condition of fasting and low metabolism - Hibernating bears as a model -

Research Project

Project/Area Number 26450455
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Integrative animal science
Research InstitutionHokkaido University

Principal Investigator

Tsubota Toshio  北海道大学, 獣医学研究科, 教授 (10207441)

Co-Investigator(Kenkyū-buntansha) 佐鹿 万里子  北海道大学, 獣医学研究科, 助教 (30722954)
下鶴 倫人  北海道大学, 獣医学研究科, 准教授 (50507168)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsツキノワグマ / 冬眠 / 心拍数 / 体温 / 妊娠 / 擬妊娠 / ロガー / 肥満 / 脂肪 / アディポネクチン / クマ / 低代謝状態 / 繁殖 / 出産 / 哺育 / 体脂肪
Outline of Final Research Achievements

Heart rate (HR) and subcutaneous body temperature (BT) were being monitored by using data loggers (DST milli-HRT, Star:Oddi) for the measurement of HR and BT, which were implanted at the breast region, for about 6 months during winter season including pre-hibernation, hibernation and post-hibernation periods. In January, pregnancy diagnosis was done by using ultrasonography for these 5 bears. Notable findings were relationships between HR and BT in pregnant bears: both HR and BT during pre-hibernation period (delayed implantation period) changed with about 24 hours cycle, BT maintained relatively high and HR exhibited some spike during hibernation period (fetal development period) and both synchronized fluctuation with multi-day cycles during post-hibernation period (natal development period).

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (9 results)

All 2016 2015 2014 Other

All Presentation (6 results) (of which Int'l Joint Research: 1 results,  Invited: 3 results) Book (2 results) Remarks (1 results)

  • [Presentation] 飼育下ツキノワグマにおける冬眠前および冬眠中の体温および心拍数の変化2016

    • Author(s)
      坪田敏男,鈴木信吾,宮城太輔,山﨑晃司,佐鹿万里子,下鶴倫人
    • Organizer
      第22回日本野生動物医学会大会
    • Place of Presentation
      宮崎市民プラザ(宮崎市)
    • Year and Date
      2016-09-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] Changes in body temperature and heart rate related with hibernation in captive Japanese black bears (Ursus thibetanus japonicus)2016

    • Author(s)
      Toshio TSUBOTA, Shingo SUZUKI, Daisuke MIYAGI, Koji YAMAZAKI, Mariko SASHIKA and Michito SHIMOZURU
    • Organizer
      The 24th International Conference on Bear Research and Management
    • Place of Presentation
      アンカレッジ,アメリカ合衆国
    • Year and Date
      2016-06-13
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ツキノワグマにおける冬眠期の皮下体温、腹腔内体温および活動量測定の試み2015

    • Author(s)
      鈴木信吾、山崎晃司、佐鹿万里子、下鶴倫人
    • Organizer
      第158回日本獣医学会学術集会
    • Place of Presentation
      北里大学(十和田)
    • Year and Date
      2015-09-07
    • Related Report
      2015 Research-status Report
  • [Presentation] ヒグマの冬眠の話2015

    • Author(s)
      下鶴倫人
    • Organizer
      CISEネット・サイエンステーリング円山動物園
    • Place of Presentation
      札幌市円山動物園
    • Year and Date
      2015-02-21
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] ヒグマの冬眠の話2014

    • Author(s)
      坪田敏男
    • Organizer
      CISEネット・サイエンステーリング円山動物園
    • Place of Presentation
      札幌市円山動物園
    • Year and Date
      2014-10-18
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 野生動物医学からクマへのアプローチ~飼育下実験、死体分析およびフィールドワーク~2014

    • Author(s)
      坪田敏男
    • Organizer
      第20回日本野生動物医学大会
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2014-09-16 – 2014-09-19
    • Related Report
      2014 Research-status Report
    • Invited
  • [Book] ホルモンから見た生命現象と進化2016

    • Author(s)
      坪田敏男
    • Total Pages
      180
    • Publisher
      裳華房
    • Related Report
      2016 Annual Research Report
  • [Book] ホルモンから見た生命現象と進化 第6巻回遊・渡りー巡ー2016

    • Author(s)
      坪田敏男
    • Total Pages
      180
    • Publisher
      裳華房
    • Related Report
      2015 Research-status Report
  • [Remarks] 野生動物学教室

    • URL

      http://wildlife.vetmed.hokudai.ac.jp/

    • Related Report
      2016 Annual Research Report 2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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