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Molecular biological analysis of W chromosome of lepidopteran insects

Research Project

Project/Area Number 26450464
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Insect science
Research InstitutionTokyo University of Agriculture and Technology

Principal Investigator

Abe Hiroaki  東京農工大学, (連合)農学研究科(研究院), 助教 (80222660)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsカイコ / 性染色体 / 転移因子 / トランスポゾン / レトロトランスポゾン / Bombyx mori / W染色体 / 鱗翅目 / 昆虫 / イチジクカサン / 動く遺伝子 / RAPD
Outline of Final Research Achievements

Sex chromosomes of the silkworm, Bombyx mori, are designated as ZW (XY) for females and ZZ (XX) for males. The female mode of development is determined by the presence of a single W chromosome. No genes for morphological traits have been mapped to the W chromosome. Many long terminal repeat (LTR) and non-LTR retrotransposons, retroposons, DNA transposons, and their derivatives, had accumulated as strata on the W chromsosome. It is notable that some of these transposable elements contained the Bombyx short interspersed element (Bm1) sequences in the elements.
A mutant strain (op mutant) of the silkworm, Bombyx mori, was proposed as a model for Parkinson's disease. A previously reported study movie documenting occasional unique actions of op/op larvae was considered; it revealed that these actions were simply reactions to the touch of other larvae. Moreover, xanthine oxidase injection did not rescue the phenotype of op mutant larvae.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (5 results)

All 2017 2016 2015 2014

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 2 results,  Acknowledgement Compliant: 2 results) Presentation (1 results) Book (1 results)

  • [Journal Article] Structural analysis of spontaneous Z-W translocations in the silkworm, Bombyx mori2016

    • Author(s)
      Tsuguru Fujii, Akio Ohnuma, Yutaka Banno, Hiroaki Abe
    • Journal Title

      Journal of Insect Biotechnology and Sericology

      Volume: 85 Pages: 79-85

    • NAID

      130005286838

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Reconsideration of the abnormal larval behaviors used to characterize a strain of the silkworm Bombyx mori as a model of Parkinson’s disease2016

    • Author(s)
      Hiroaki Abe
    • Journal Title

      Trends in Entomology

      Volume: 12 Pages: 81-90

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Positional cloning of the sex-linked giant egg (Ge) locus in the silkworm, Bombyx mori.2015

    • Author(s)
      Fujii T, Abe H, Kawamoto M, Banno Y, Shimada T.
    • Journal Title

      Insect Molecular Biology

      Volume: 24 Issue: 2 Pages: 213-221

    • DOI

      10.1111/imb.12150

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] ヒトのパーキンソン病のモデルとされるカイコの動きを再考した2017

    • Author(s)
      阿部 広明
    • Organizer
      第61回日本応用動物昆虫学会大会
    • Place of Presentation
      東京農工大学小金井キャンパス・東京都・小金井市
    • Year and Date
      2017-03-28
    • Related Report
      2016 Annual Research Report
  • [Book] Short Views on Insect Biochemistry and Molecular Biology2014

    • Author(s)
      Hiroaki Abe, Tsuguru Fujii and Raman Chandrasekar
    • Total Pages
      770
    • Publisher
      International Book Mission, Academic Publisher, South India.
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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