Identification of novel bioactive peptides to modulate feeding behavior in insects.
Project/Area Number |
26450471
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Insect science
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Research Institution | University of Miyazaki |
Principal Investigator |
Ida Takanori 宮崎大学, 産業動物防疫リサーチセンター, 准教授 (00381088)
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Co-Investigator(Renkei-kenkyūsha) |
Mamiko Ozaki 神戸大学, 理学研究科, 教授 (00314302)
Kume Kazuhiko 名古屋市立大学, 薬学部, 教授 (30251218)
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Research Collaborator |
Hatsumi Tominaga 宮崎大学, フロンティア科学実験総合センター, 技能補佐員
Eri iWamoto 宮崎大学, フロンティア科学実験総合センター, 技能補佐員
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Project Period (FY) |
2014-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 新規生理活性ペプチド / オーファン受容体 / 昆虫 / 摂食行動 / 新規生理活性ペプチドの発見 / オーファンGPCR / モデル生物 / 生理活性ペプチド |
Outline of Final Research Achievements |
The purpose of this research is hunting of novel bioactive peptides and elucidation of physiological role of these peptides in arthropod. Especially, I try to elucidate the feeding behavior for these peptides, and aim at disinfestation of a harmful insect and efficient upbringing of the useful arthropod. As a result, we found five novel bioactive peptides for drosophila orphan receptors. We clarified CCHamide secreted from fat body affected to insulin producing cell in the brain, and modulated secretion of insulin-like peptide, then controlled growth. In addition, we clarified dRYamide had strong anorexigenic activity in fly and prawn. These functions are looking for a possibility to the industrial application.
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Report
(4 results)
Research Products
(29 results)
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[Journal Article] Suppressive effects of dRYamides on feeding behavior of the blowfly, Phormia regina2015
Author(s)
Maeda T, Nakamura Y, Shiotani H, Hojo M, Yoshii T, Ida T, Sato T, Yoshida M, Miyazato M, Kojima M, Ozaki M
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Journal Title
Zoological Letters
Volume: 1
Issue: 1
Pages: 1-10
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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