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Aluminum toxicity and membrane lipid

Research Project

Project/Area Number 26450483
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Environmental agriculture(including landscape science)
Research InstitutionNihon University

Principal Investigator

SUNAIRI Michio  日本大学, 生物資源科学部, 教授 (80196906)

Co-Investigator(Renkei-kenkyūsha) AIZAWA Tomoko  日本大学, 生物資源科学部, 助教 (60398849)
Research Collaborator OOHARA Natsuki  
SHIINA Ayano  
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords環境適応 / アルミニウム耐性 / アルミニウム毒性
Outline of Final Research Achievements

Aluminum ion (Al) severely inhibits plant growth in acid soils. Although it has been proposed that the mechanisms of Al toxicity might be related to oxidative stresses, turbulences in functions of membrane lipids, or disturbances in metal ion homeostasis, it is still need to be clarified.
In this study, we analyzed the lipid compositions of highly Al-tolerant bacterium, Acidocella aluminiidurans, and yeast, Rhodotorula taiwanensis, and examined the relationships between their Al-tolerance and lipid compositions. In addition, Al-sensitive mutants were selected from a collection of deletion mutants (4826 strains) of Saccharomyces cerevisiae BY4741 and their mechanisms of Al-sensitivities, especially the lipid-related genes, were studied.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (3 results)

All 2016 2015

All Presentation (3 results) (of which Int'l Joint Research: 3 results)

  • [Presentation] Characterization and lipidomic analyses of highly aluminum tolerant microorganisms.2016

    • Author(s)
      moko Aizawa, Ayano Shiina, Xue Qiang Zhao, Michio Sunairi.
    • Organizer
      16th International Symposium on Microbial Ecology (ISME 2016)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Year and Date
      2016-08-21
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Whichcellular components or processes are relevant with aluminum toxicity?2016

    • Author(s)
      Ayano Shiina, Tomoko Aizawa, Xue Qiang Zhao, Michio Sunairi.
    • Organizer
      16th International Symposium on Microbial Ecology (ISME 2016)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Year and Date
      2016-08-21
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Aluminum toxicity and tolerance in microorganisms2015

    • Author(s)
      Aizawa-Urai T, Zhao XQ, Sato J, Ohara N, Shiina A, Sunairi M.
    • Organizer
      FEMS 2015
    • Place of Presentation
      Maastrichit, Netherlands
    • Year and Date
      2015-06-09
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research

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Published: 2014-04-04   Modified: 2018-03-22  

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