Aluminum toxicity and membrane lipid
| Project/Area Number |
26450483
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Environmental agriculture(including landscape science)
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| Research Institution | Nihon University |
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Principal Investigator |
SUNAIRI Michio 日本大学, 生物資源科学部, 教授 (80196906)
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| Co-Investigator(Renkei-kenkyūsha) |
AIZAWA Tomoko 日本大学, 生物資源科学部, 助教 (60398849)
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| Research Collaborator |
OOHARA Natsuki
SHIINA Ayano
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 環境適応 / アルミニウム耐性 / アルミニウム毒性 |
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| Outline of Final Research Achievements |
Aluminum ion (Al) severely inhibits plant growth in acid soils. Although it has been proposed that the mechanisms of Al toxicity might be related to oxidative stresses, turbulences in functions of membrane lipids, or disturbances in metal ion homeostasis, it is still need to be clarified.
In this study, we analyzed the lipid compositions of highly Al-tolerant bacterium, Acidocella aluminiidurans, and yeast, Rhodotorula taiwanensis, and examined the relationships between their Al-tolerance and lipid compositions. In addition, Al-sensitive mutants were selected from a collection of deletion mutants (4826 strains) of Saccharomyces cerevisiae BY4741 and their mechanisms of Al-sensitivities, especially the lipid-related genes, were studied.
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Report
(4 results)
Research Products
(3 results)
