| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
In this project, improvement of our NHC ligand was pursued. Although the installation of a pendent coordinating functionality near the carbene carbon was failed, introduction of electron-withdrawing groups at the remote positions was successful to improve the regio selectivity in the allylic substitution reaction. In addition, chiral guanidine catalyst was designed on the basis of the chair NHC ligand. The catalyst showed an excellent performance in the asymmetric addition reaction of diketones to nitro olefins.
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