Nanoparticle-based pulmonary drug delivery system to extend the nanomedicine
Project/Area Number |
26460040
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Physical pharmacy
|
Research Institution | Nagoya City University |
Principal Investigator |
Tetsuya Ozeki 名古屋市立大学, 大学院薬学研究科, 教授 (60277259)
|
Co-Investigator(Kenkyū-buntansha) |
田上 辰秋 名古屋市立大学, 大学院薬学研究科, 講師 (10609887)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | ナノコンポジット粒子 / 経肺投与 / ドラッグデリバリーシステム / 吸入剤 / 機能性ナノ粒子 / 金ナノ粒子 / 経肺投与型製剤 |
Outline of Final Research Achievements |
Various kinds of nanoparticle-based formulations, which are termed as nanomedicine, have been developing among researchers. However, most of nanomedicine is applied for intravenous injection and the administration route is a limitation for the principal use of nanomedicine. I have been developing various nanocomposite particles (microparticles containing functional nanoparticles) by using spray drying technology. The functional nanoparticles are expecting for not only lung-related diseases but also systemic diseases by passing through alveolar endothelial cells layer which is in the deepest lung tissue. I developed the composite particles containing ultra small gold nanoparticles or curcumin as poorly water soluble compound and then the nanocomposite particles were evaluated.
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Report
(4 results)
Research Products
(9 results)