| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
|---|
| Outline of Final Research Achievements |
Genus Panax (Araliaceae), widely known as Ginseng genus, is one of the most important medicinal genera. The underground parts of almost all species in the genus are traditionally-used as medicines, including three highly-esteemed ones as Ginseng, American Ginseng and Notoginseng. Triterpene saponins, generally referred to as ginsenosides, are bioactive constituents of Ginseng drugs. Each Panax species has its own characteristic saponin composition. In this study, three Panax species with closely phylogenetical relationship but with quite different chemical compositions were focused on as representatives. Deep transcriptome analysis by next-generation DNA sequencer has been conducted on the three species to explore the molecular basis responsible for the formation of chemical diversity within genus Panax. The genes involved in biosynthetic pathway of triterpene production from the three species were compared.
|
