Development and application of assay systems for searching antipruritic drug.
| Project/Area Number |
26460138
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Natural medicines
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| Research Institution | Mukogawa Women's University |
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Principal Investigator |
Oku Hisae 武庫川女子大学, 薬学部, 准教授 (90281518)
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| Co-Investigator(Kenkyū-buntansha) |
石黒 京子 武庫川女子大学, 薬学部, 教授 (70151363)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 抗かゆみ物質 / 天然資源 / アッセイ法 / 淤血 / ストレス / 抗かゆみ / 病態モデル / マウス |
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| Outline of Final Research Achievements |
By the disease with serious itches such as atopic dermatitis, stress and blood stasis are a trigger to turn the worse and intractable. Therefore, we demonstrated the relationship blood stasis, stress and worse of itch by making full use of the blood stasis model mice which developed originally. Furthermore, we identified the proteins which may be new treatment target factor for a patient with the itch sensitive skin (itchy skin), and found the seeds plant for searching antipruritic compounds.
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Report
(4 results)
Research Products
(10 results)
