Establishment of optimization method of antimicrobial agent therapy based on the therapeutic goal achievement probability of target organs
Project/Area Number |
26460198
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Medical pharmacy
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Research Institution | Hiroshima University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
池田 佳代 広島大学, 医歯薬保健学研究院(薬), 助教 (30379911)
猪川 和朗 広島大学, 医歯薬保健学研究院(薬), 准教授 (40363048)
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Project Period (FY) |
2014-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
|
Keywords | 臨床 / 感染症 / 抗菌剤 / PK/PD / PK/PD |
Outline of Final Research Achievements |
We reported the therapeutic drug monitoring of voriconazole in Japanese patients used analysis based on clinical practice data. We reported the pharmacokinetic/pharmacodynamic analysis of teicoplanin in patients with MRSA infections. We reported the pharmacokinetics of ampicillin-sulbactam in anuric patients used dosing optimization for prophylaxis during cardiovascular surgery.
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Report
(4 results)
Research Products
(9 results)
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[Journal Article] Penetration of piperacillin-tazobactam into human prostate tissue and dosing considerations for prostatitis based on site-specific pharmacokinetics and pharmacodynamics.2015
Author(s)
Kobayashi I, Ikawa K, Nakamura K, Nishikawa G, Kajikawa K, Yoshizawa T, Watanabe M, Kato Y, Zennami K, Kanao K, Tobiume M, Yamada Y, Mitsui K, Narushima M, Morikawa N, Sumitomo M.
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Journal Title
J. Infect. Chemother.
Volume: 21
Issue: 8
Pages: 575-580
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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