| Project/Area Number |
26460216
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical pharmacy
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| Research Institution | The University of Tokyo |
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Principal Investigator |
SATOH Hiroki 東京大学, 大学院薬学系研究科(薬学部), 特任准教授 (80451855)
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| Co-Investigator(Kenkyū-buntansha) |
澤田 康文 東京大学, 大学院薬学系研究科(薬学部), 客員教授 (80114502)
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| Research Collaborator |
NAKAJIMA Hitomi
IKARASHI Shohei
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 薬物有害事象 / 薬物間相互作用 / 地域薬局 / 副作用 / 相互作用 / 市販後情報収集 |
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| Outline of Final Research Achievements |
We constructed a system for collecting information of adverse drug reactions and drug-drug interactions, which a pharmacist in community pharmacy heard from patients in clinical pharmaceutical care. In this system, a total of 5,379 cases of adverse drug reactions or drug-drug interactions were gathered in the regional pharmacy group. Based on the collected informations, we developed an algorithm to evaluate an adverse drug reactions risk in the case of drowsiness, dizziness, lightheadedness, and blood pressure drop and that in the case of urinary retention, difficulty of urination, dry mouth, and constipation. The risk points of adverse drug reactions calculated by this algorithm significantly associated with the severity of adverse drug reactions in cases.
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