| Project/Area Number |
26460228
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical pharmacy
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| Research Institution | Nagoya City University |
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Principal Investigator |
Kikuchi Chigusa 名古屋市立大学, 大学院薬学研究科, 講師 (20444987)
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| Co-Investigator(Kenkyū-buntansha) |
梶栗 潤子 名古屋市立大学, 大学院医学研究科, 研究員 (10444986)
鈴木 匡 名古屋市立大学, 大学院薬学研究科, 教授 (20555081)
今枝 憲郎 名古屋市立大学, 大学院医学研究科, 准教授 (30347398)
松永 民秀 名古屋市立大学, 大学院薬学研究科, 教授 (40209581)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 糖尿病 / 性差医療 / 血管障害 / 健診受診 / 検体測定室 / 性差 / 酸化ストレス |
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| Outline of Final Research Achievements |
In this study, we examined vascular endothelium function using diabetes model animals and questionnaire on factors of going for a medical checkup for women to clarify the mechanism of vascular endothelium dysfunction mediated by sex difference. In diabetes model female rats, post-occlusive hind limb reactive hyperemia index was decreased as compared with control rats at early stage. As the result of the questionnaire, many women were under stress. It was suggested that especially child rearing and economic factors prevent women from going for a medical checkup.
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