Design of transdermal ophthalmic therapy using drug nanoparticle technology and application of it as eye infection treatment
Project/Area Number |
26460243
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Medical pharmacy
|
Research Institution | Kindai University |
Principal Investigator |
|
Co-Investigator(Renkei-kenkyūsha) |
NAGAI Noriaki 近畿大学, 薬学部, 講師 (90411579)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | 貼付型眼瞼透過型製剤 / 抗菌薬 / ナノ粒子 / 界面活性剤 / マイボーム腺 / レボフロキサシン / アクリル酸ポリマー / マイバム / 薬物安定性 / 家兎 |
Outline of Final Research Achievements |
We developed the transdermal drug delivery system for ophthalmic therapy by using drug nanoparticle technology (transdermal ophthalmic therapy). The “transdermal ophthalmic therapy” show non-stimulate, and can provide stable drug supply to lacrimal fluid via meibomian glands. This preparation may lead to an expansion of their usefulness for therapy in the ophthalmologic field.
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Report
(4 results)
Research Products
(9 results)