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Investigation of the Pharmaceutical pollution in the pharmacy and the health impact assessment of occupational exposure

Research Project

Project/Area Number 26460247
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical pharmacy
Research InstitutionHiroshima International University

Principal Investigator

MAEDA SHIZUKO  広島国際大学, 薬学部, 助教 (80435065)

Co-Investigator(Kenkyū-buntansha) 杉原 数美  広島国際大学, 薬学部, 教授 (20271067)
塚本 豊久  広島国際大学, 薬学部, 教授 (40389101)
佐和 章弘  広島国際大学, 薬学部, 教授 (70389104)
田山 剛崇  広島国際大学, 薬学部, 准教授 (80389121)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords医薬品汚染 / 医薬品曝露 / 医薬品粉じん / 後発医薬品 / 散剤調剤 / 帯電量 / 錠剤粉砕 / 環境汚染
Outline of Final Research Achievements

We conducted the model experiments for the indoor air pollution by the pharmaceutical dusts from dispensing powders.And we examined whether it is possible to reduce the pollution by using an air cleaner.Furthermore,to change it to medicine with a little exposure more,we compared the original medicine and the generic medicines about physical properties.In addition,we performed the questionnaire to 721 pharmacists for the pharmaceutical pollution.
Results from the model experiment revealed the pharmaceutical dusts were scattered in the air by dispensing powder and it could be reduced by using an air cleaner.About the comparison between the original medicine and the generic medicines,medicine of the smaller particle size was easy to be scattered.From the results of the questionnaire,it is revealed there are more than 70% of pharmacists who are worrying about pharmaceutical exposure by dispensing powder.Our results should be helpful in reducing the pharmaceutical pollution in the pharmacy.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (5 results)

All 2016 2015

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (4 results)

  • [Journal Article] Estimation of occupational exposure to drugs during tablet crushing2016

    • Author(s)
      Shizuko Maeda , Eiko Takahashi , Yoshitaka Tayama , Shigeyuki Kitamura , Toyohisa Tsukamoto , Katsushi Miyake , Kazumi Sugihara
    • Journal Title

      Fundamental Toxicological Sciences

      Volume: 3 Issue: 4 Pages: 177-183

    • DOI

      10.2131/fts.3.177

    • NAID

      130005158221

    • ISSN
      2189-115X
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] ロキソプロフェンナトリウム水和物細粒の飛散性に影響を与える因子の検討2016

    • Author(s)
      前田 志津子, 土井 えりか, 手嶋 茂貴, 杉原 数美, 田山 剛崇, 三宅 勝志
    • Organizer
      第26回日本医療薬学会年会
    • Place of Presentation
      国立京都国際会館(京都市左京区)
    • Year and Date
      2016-09-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] タンニン酸アルブミンの製品間比較~帯電量調査~2016

    • Author(s)
      前田 志津子, 手嶋 茂貴, 田山 剛崇, 安原 昌子, 寺重 隆視, 杉原 数美,佐和 章弘, 三宅 勝志
    • Organizer
      日本薬学会第 136年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2016-03-27
    • Related Report
      2015 Research-status Report
  • [Presentation] 患者の残薬管理および廃棄活動に関する調査2016

    • Author(s)
      杉原 数美、前田 志津子、田山 剛崇、西村 和之、太田 茂
    • Organizer
      日本薬学会第 136年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2016-03-27
    • Related Report
      2015 Research-status Report
  • [Presentation] 先発医薬品と後発医薬品の比較:ロキソプロフェンナトリウム水和物細粒の飛散粉じん量調査2015

    • Author(s)
      前田 志津子、土井 えりか、杉原 数美、田山 剛崇、塚本 豊久
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      デザイン・クリエイティブセンター神戸(神戸市中央区)
    • Year and Date
      2015-03-26
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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