| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
We aimed to find and characterize anticancer target(s) in regulators of cell death-mode, necrosis or apoptosis, by genomic and proteomic approach. (1) Extracellular leaked proteins in necrosis or apoptosis were detected by proteomic approach; (2) Gene mutations related cell-death switching were found by whole exon sequencing; (3) We investigated the anticancer effectiveness for the previously reported cell-death regulators, and identified a possible anticancer microRNA.
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