| Project/Area Number |
26460506
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Parasitology (including sanitary zoology)
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| Research Institution | University of Fukui |
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Principal Investigator |
Yano Yasuhiro 福井大学, 学術研究院医学系部門, 助教 (60220208)
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| Co-Investigator(Kenkyū-buntansha) |
夏秋 優 兵庫医科大学, 医学部, 准教授 (60208072)
高田 伸弘 福井大学, 医学部, 客員准教授 (90003409)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 重症熱性血小板減少症候群 / マダニ / 媒介サイクル / 媒介動物 / ウイルス |
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| Outline of Final Research Achievements |
To elucidate the tick transmission cycle of severe febrile thrombocytopenic syndrome (SFTS) reported in Japan for the first time in 2013, in the fixed point survey site in the Reinan area of Fukui Prefecture and Toyooka City, Hyogo Prefecture where patients occurred, we revealed the seasonal occurrence of ticks on vegetation. Although it succeeded in detecting SFTS gene from ticks from Hyogo prefecture, it was presumed that the infection rate of ticks collected in Fukui prefecture was low. Electron microscopic observation of SFTS virus propagated in cultured cells was carried out to clarify ultrastructural features. On the other hand, skin condition around the tick-bite site, which is the infection gateway of virus invasion, was analyzed. In addition to collecting and examining tick-bite cases, we also add samples from wild animals including rodent.
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