| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
We studied to development assay utilizing aptamer for oxytocin (OXT), was shown to play important key roles in social interactions and social behavior and a series of studies investigated the relationship between autism spectrum disorder (ASD) and OXT, and applying to a clinical examination by using that assay.
As a result of SELEX, the aptamers (ssDNA) for OXT prepared in random ssDNA BANK and sequence of those were high homologous sequence. Therefore, we suggested that aptamer for OXT was selected from many ssDNA containing random sequence. Moreover, we made a measurement of OXT in Japanese human plasma on this study by using immunoassay for OXT. As a result, the average levels of males and females were 30 and 25 pg/mL respectively, here.
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