| Project/Area Number |
26460686
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
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| Research Institution | Kyorin University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
渡邊 卓 杏林大学, 医学部, 教授 (00191768)
大塚 弘毅 杏林大学, 医学部, 学内講師 (70439165)
大西 宏明 杏林大学, 医学部, 教授 (80291326)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 非結核性抗酸菌 / 全ゲノム解析 / 質量分析 |
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| Outline of Final Research Achievements |
We performed whole genome analysis and mass spectrometry of Mycobacterium kyorinense and its related mycobacterium species. M. kyorinense and its related species demonstrated common features in several drug-resistance related genes including rpoB, inhA, katG, ahpC, and embB, but full genome data were not available in these mycobacteria due to technical issues. We successfully performed mass spectrometry for these species, but they were difficult to distinguish by mass spectrometry, probably due to their high similarity of 16S rRNA between species.
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