• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Virtual nodule based on 3D spatial resolution in lung CT and its application to performance evaluation of computer-aided detection (CAD) system

Research Project

Project/Area Number 26460722
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical Physics and Radiological Technology
Research InstitutionNiigata University

Principal Investigator

OHKUBO Masaki  新潟大学, 医歯学系, 教授 (10203738)

Co-Investigator(Kenkyū-buntansha) 和田 真一  新潟大学, 医歯学系, 教授 (80105519)
Research Collaborator MATSUMOTO Toru  健生クリニック
MURAO Kohei  富士通(株)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2015: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywordsエックス線CT / 変調伝達関数(MTF) / 点広がり関数(PSF) / 空間分解能 / 肺がん / コンピュータ支援診断(CAD) / 模擬結節 / X線CT装置 / CT検診
Outline of Final Research Achievements

We proposed an application of virtual nodules to evaluate the performance of computer-aided detection (CAD) of lung cancer CT screening. When a CAD system is introduced in an institution providing CT screening, its performance should be evaluated by image data obtained under the same scan and image reconstruction conditions as those used at that site, because CAD performance is affected by CT scanning and image reconstruction conditions. The virtual nodules were generated based on the spatial resolution of a CT system used in an institution providing cancer screening and were fused into lung images obtained at that institution, allowing site specificity. The detection limits of a CAD system were determined in terms of the size and density of lung nodules. This methodology for guiding the detection limit might be a useful evaluation strategy. Virtual nodules can be an effective means of evaluating site-specific CAD performance.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (28 results)

All 2017 2016 2015 2014 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Acknowledgement Compliant: 3 results,  Open Access: 2 results) Presentation (22 results) (of which Int'l Joint Research: 4 results) Remarks (2 results)

  • [Journal Article] A method for evaluating the performance of computeraided detection of pulmonary nodules in lung cancer CT screening: detection limit for nodule size and density2017

    • Author(s)
      Kobayashi H, Ohkubo M, Narita A, Marasinghe JC, Murao K, Matsumoto T, Sone S, Wada S
    • Journal Title

      BJR

      Volume: 90 Issue: 1070 Pages: 1-10

    • DOI

      10.1259/bjr.20160313

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Image filtering to make computer-aided detection robust to image reconstruction kernel choice in lung cancer CT screening2016

    • Author(s)
      Ohkubo M, Narita A, Wada S, Murao K, Matsumoto T.
    • Journal Title

      Med Phys

      Volume: 43 Issue: 7 Pages: 4098-4105

    • DOI

      10.1118/1.4953247

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Measurement of the Dose Rate Using Dosimeters in Interventional Radiology and Its Difficulty2016

    • Author(s)
      吉田 秀義, 高橋 千春,成田 信浩, 水沢 康彦, 関谷 勝, 大久保 真樹
    • Journal Title

      Japanese Journal of Radiological Technology

      Volume: 72 Issue: 1 Pages: 63-72

    • DOI

      10.6009/jjrt.2016_JSRT_72.1.63

    • NAID

      130005120261

    • ISSN
      0369-4305, 1881-4883
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Feasible method to assess the performance of a lung cancer CT screening CAD system in clinical practice: dependence on nodule size and density2014

    • Author(s)
      Marasinghe JC, Ohkubo M, Kobayashi H, Murao K, Matsumoto T, Sone S, Wada S
    • Journal Title

      International Journal of Medical Physics, Clinical Engineering and Radiation Oncology

      Volume: 3 Issue: 02 Pages: 107-116

    • DOI

      10.4236/ijmpcero.2014.32016

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] 3D-PSF模擬結節を用いた胸部CT-CADの性能特性評価の研究 :結節性状と画像再構成条件の変化に対するCADの応答2017

    • Author(s)
      郷戸 允, 大久保 真樹, 成田 啓廣, 菅原 秀賢, 村松 禎久, 村尾 晃平, 松本 徹, 和田 真一
    • Organizer
      第24回日本CT検診学会
    • Place of Presentation
      あわぎんホール(徳島県徳島市)
    • Year and Date
      2017-02-03
    • Related Report
      2016 Annual Research Report
  • [Presentation] Accurate volume measurement for lung nodule in CT image by deconvolution method2016

    • Author(s)
      Sugawara H, Narita A, Ohkubo M, Wada S
    • Organizer
      第111回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-04-14
    • Related Report
      2016 Annual Research Report 2015 Research-status Report
  • [Presentation] Generating nodule-like object functions for evaluating CAD performance in lung cancer CT screening2016

    • Author(s)
      Narita A, Ohkubo M, Wada S
    • Organizer
      第111回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-04-14
    • Related Report
      2016 Annual Research Report 2015 Research-status Report
  • [Presentation] Generating nodule-like object functions for CAD performance evaluation in lung cancer screening: feasibility study2016

    • Author(s)
      Narita A, Ohkubo M, Wada S
    • Organizer
      2016 AAPM Spring Clinical Meeting
    • Place of Presentation
      Grand America Hotel (Salt lake City, USA)
    • Year and Date
      2016-03-05
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 肺がんCT検診におけるCAD性能評価を目的としたnodule-like obiect functionの生成2016

    • Author(s)
      成田 啓廣,大久保 真樹,和田 真一
    • Organizer
      平成27年度第5回がんプロセミナー(新潟大学・東北大学合同 放射線治療・医学物理セミナー)
    • Place of Presentation
      新潟医療人育成センター(新潟県新潟市)
    • Year and Date
      2016-01-30
    • Related Report
      2015 Research-status Report
  • [Presentation] Feasibility study for application of nodule-like object function to accurate volume rneasurement of nodule in lung cancer CT screening2016

    • Author(s)
      菅原 秀賢,大久保 真樹,成田 啓廣,和田 真一
    • Organizer
      平成27年度第5回がんプロセミナー(新潟大学・東北大学合同 放射線治療・医学物理セミナー)
    • Place of Presentation
      新潟医療人育成センター(新潟県新潟市)
    • Year and Date
      2016-01-30
    • Related Report
      2015 Research-status Report
  • [Presentation] Influence of nodule offset in CAD performance evaluation of lung cancer CT screening: A virtual nodule study2015

    • Author(s)
      Nuwan DMl, Wada S, Ohkobo M, Yoshida A, Kobayashi H
    • Organizer
      Peradeniya University International Research Sessions(iPURSE) 2015
    • Place of Presentation
      Peradeniya University (Sri Lanka)
    • Year and Date
      2015-11-05
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effect of reconstruction kernel and slice thickness on performance of CAD software used in the screening of lung cancer2015

    • Author(s)
      Munaweera CM, Wada S, Ohkubo M, Jayasinghe RD
    • Organizer
      Peradeniya University International Research Sessions(iPURSE) 2015
    • Place of Presentation
      Peradeniya University (Sri Lanka)
    • Year and Date
      2015-11-05
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 放射線治療計画CT三次元空間分解能が治療計画精度に及ぼす影響の研究2015

    • Author(s)
      重田 尚吾,字都宮 悟,棚邊 哲史,早川 岳英,沼田 彩美,大久保 真樹,和田 真一,青山 英史,笹本 龍太
    • Organizer
      第5回東北放射線医療技術学術大会
    • Place of Presentation
      山形テルサ(山形県山形市)
    • Year and Date
      2015-10-31
    • Related Report
      2015 Research-status Report
  • [Presentation] CT画像における総合的画質評価法に関する検討―体軸方向空間分解能を用いた新たな被写体の設定―2015

    • Author(s)
      吉田 皓文,成田 啓廣,長谷川 晃,田崎 かおり,大久保 真樹,和田 真一,能登 義幸
    • Organizer
      第43回日本放射線技術学会秋季学術大会
    • Place of Presentation
      金沢市文化ホール(石川県金沢市)
    • Year and Date
      2015-10-08
    • Related Report
      2015 Research-status Report
  • [Presentation] Validation of Virtual&Nodules for Evaluating the Performance of Computer' Aided Detection (CAD) System in Lung Cancer CT Screening.2015

    • Author(s)
      Ehalagasthanna NT, Marasinghe JC, Kobayashi H, Ohkubo M, Wada S
    • Organizer
      Third Conference on Sri Lanka - Japan Collaborative Research 2015(SLJCR-2015)
    • Place of Presentation
      Peradeniya University (Sri Lanka)
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 放射線治療計画CT3次元空間分解能が治療計画精度に及ぼす影響の研究2015

    • Author(s)
      重田 尚吾,笹本 龍太,宇都 宮悟,棚邊 哲史,早川 岳英,沼田 彩美,大久保 真樹,青山 英史,和田 真一
    • Organizer
      第1回がん治療・医学物理合同研究セミナー
    • Place of Presentation
      新潟大学医学部(新潟県新潟市)
    • Year and Date
      2015-08-22
    • Related Report
      2015 Research-status Report
  • [Presentation] CT検診肺内結節画像の空間分解能変換を用いたデータベース化2015

    • Author(s)
      成田 啓廣,大久保 真樹,和田 真一
    • Organizer
      第1回がん治療・医学物理合同研究セミナー
    • Place of Presentation
      新潟大学医学部(新潟県新潟市)
    • Year and Date
      2015-08-22
    • Related Report
      2015 Research-status Report
  • [Presentation] Influence of spatial resolution of computed tomography on radiation treatment planning: a feasibility study with pulmonary nodule image simulation.2015

    • Author(s)
      Shigeta S, Sasamoto R, Utsunomiya S, Ohkubo M, Tanabe S, Aoyama H, Wada S
    • Organizer
      第109回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2015-04-16 – 2015-04-19
    • Related Report
      2014 Research-status Report
  • [Presentation] Influence of spatial resolution of computed tomography on radiation treatment planning: a feasibility study with pulmonary nodule image simulation.2015

    • Author(s)
      Shigeta S, Sasamoto R, Utsunomiya S, Ohkubo M, Tanabe S, Aoyama H, Wada S
    • Organizer
      第109回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-04-16
    • Related Report
      2015 Research-status Report
  • [Presentation] Quality assurance of lung cancer CT screening CAD system by applying PSF-based reference virtual nodule set.2015

    • Author(s)
      Marasinghe JC, Ohkubo M, Kobayashi H, Yoshida A, Murao K, Matsumoto T, Sone S, Wada S
    • Organizer
      European Congress of Radiology 2015
    • Place of Presentation
      Vienna(Austria)
    • Year and Date
      2015-03-04 – 2015-03-08
    • Related Report
      2014 Research-status Report
  • [Presentation] Characterization of the model-based iterative reconstruction algorithm: Confirmation of coexistence of dose reduction and spatial resolution improvement2015

    • Author(s)
      Kayugawa A, Noto Y, Taga T, Fukaya T, Tasaki K, Fujioka T, Ohkubo M
    • Organizer
      European Congress of Radiology 2015
    • Place of Presentation
      Vienna(Austria)
    • Year and Date
      2015-03-04 – 2015-03-08
    • Related Report
      2014 Research-status Report
  • [Presentation] 胸部CT検診CADのQAに関する研究:ファントム模擬結節による virtual nodule offset の検証2015

    • Author(s)
      吉田 皓文,大久保 真樹,Marasinghe Janaka C.,村尾 晃平,松本 徹,和田 真一
    • Organizer
      第22回日本CT検診学会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2015-02-13 – 2015-02-14
    • Related Report
      2014 Research-status Report
  • [Presentation] 放射線治療計画用CTの空間分解能が線量計算に及ぼす影響2014

    • Author(s)
      重田 尚吾,笹本 龍太,大久保 真樹,和田 真一,宇都宮 悟,棚邊 哲史,青山 英史
    • Organizer
      第115回新潟臨床放射線学会
    • Place of Presentation
      新潟大学医学部第2講義室(新潟市)
    • Year and Date
      2014-12-20
    • Related Report
      2014 Research-status Report
  • [Presentation] Virtual noduleを用いた胸部CT検診CAD-QAにおけるnodule offsetの影響:ファントム模擬結節による検証2014

    • Author(s)
      吉田 皓文,大久保 真樹,Marasinghe JC,村尾 晃平,松本 徹,和田 真一
    • Organizer
      第4回東北放射線医療技術学術大会
    • Place of Presentation
      朱鷺メッセ(新潟市)
    • Year and Date
      2014-10-25 – 2014-10-26
    • Related Report
      2014 Research-status Report
  • [Presentation] Validation of using PSF-based virtual nodules to assess the basic performances of lung cancer CT screening CAD system2014

    • Author(s)
      Marasinghe JC, Ohkubo M, Wada S, Kobayashi H, Yoshida A, Murao K, Matsumoto T, Sone S
    • Organizer
      Computer Assisted Radiology and Surgery 2014
    • Place of Presentation
      Fukuoka Convention Center(福岡市)
    • Year and Date
      2014-06-25 – 2014-06-28
    • Related Report
      2014 Research-status Report
  • [Presentation] Influence of nodule offset in CAD performance evaluation of lung cancer CT screening2014

    • Author(s)
      Yoshida A, Ohkubo M, Kobayashi H, Marasinghe JC, Nuwan DMJ , Murao K, Matsumoto T, Sone S, Wada S
    • Organizer
      第107回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-04-10 – 2014-04-13
    • Related Report
      2014 Research-status Report
  • [Remarks] 新潟大学医学部保健学科大学院保健学研究科 研究紹介

    • URL

      http://www.clg.niigata-u.ac.jp/kenkyuka/kenkyu-shokai/#2

    • Related Report
      2016 Annual Research Report
  • [Remarks] 新潟大学医学部保健学科・大学院保健学研究科 研究紹介2

    • URL

      http://www.clg.niigata-u.ac.jp/kenkyuka/kenkyu-shokai/

    • Related Report
      2015 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi