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Establishment of attenuation correction method using myocardial gated X-ray/CT imaging in integrated SPECT/CT system

Research Project

Project/Area Number 26460725
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical Physics and Radiological Technology
Research InstitutionKanazawa University

Principal Investigator

ONOGUCHI Masahisa  金沢大学, 保健学系, 教授 (30283120)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords心筋動態ファントム / 心電図同期SPECT / SPECT/CT装置 / 減弱補正 / 心機能 / 心筋血流 / 心電図同期CT撮影法 / 被ばく線量 / 心臓動態ファントム / 心電図同期心筋SPECT
Outline of Final Research Achievements

The conventional dynamic cardiac phantom used in the field of nuclear medicine has a structure for which the size of the external side of the heartis fixed and only the inner side moves anteroposterior. Therefore, its usefulness in technical evaluation is limited. Hence, we developed a new dynamic cardiac phantom in which the outer and inner membranes freely move. Using a SPECT/CT system, we performed validation by filling the myocardial layer of the dynamic cardiac phantom with solution and the ventricle part with contrast medium. We evaluated myocardial wall motions of 3 segments (basal, mid, and apical) by setting the stroke ratios at 20:20 (ventricle-to-myocardial layer ratio). The myocardial wall motions at the stroke ratio of 20:20 were 7.50 ± 0.44, 11.15 ± 0.56, and 9.90 ± 0.24 mm in the basal, mid, and apical segments, respectively. These results suggest that the use of this phantom can realize technical evaluation that presumes various clinical conditions.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (20 results)

All 2016 2015 2014 Other

All Journal Article (7 results) (of which Peer Reviewed: 6 results,  Acknowledgement Compliant: 5 results,  Open Access: 1 results) Presentation (11 results) (of which Int'l Joint Research: 3 results,  Invited: 1 results) Remarks (2 results)

  • [Journal Article] Development of a Two-layer Dynamic Cardiac Phantom with a Double Pump2016

    • Author(s)
      Hara N, Onoguchi M, Hojyo O, Kawaguchi H, Murai M, Matsushima N
    • Journal Title

      J Nucl Med Technol

      Volume: 44 Pages: 31-35

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Development of a myocardial phantom and analysis system toward the standardization of myocardial SPECT image across institutions2016

    • Author(s)
      Takayuki Shibutani, Masahisa Onoguchi, Tetsuro Katafuchi, Seigo Kinuya
    • Journal Title

      Ann Nucl Med

      Volume: 30 Pages: 699-707

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Technical aspects Image reconstruction2016

    • Author(s)
      Onoguchi M, Konishi T, Shibutani T, Matsuo S, Nakajima K
    • Journal Title

      Ann Nucl Cardiol

      Volume: 2 Pages: 68-72

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Optimization of the pre-filter parameters by myocardial perfusion SPECT: The formulation of flowchart2016

    • Author(s)
      Shibutani T, Onoguchi M, Yamada T, Kamida H, Kunishita K, Hayashi Y, Nakajima T
    • Journal Title

      Australas Phys Eng Sci Med

      Volume: 39 Pages: 571-581

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a 2-Layer Double-Pump Dynamic Cardiac Phantom2016

    • Author(s)
      Hara Narihiro, Onoguchi Masahisa, Hojyo Osamu
    • Journal Title

      Journal of Nuclear Medicine Technology

      Volume: 44 Pages: 31-35

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] The reproducibility of time-of-flight PET and conventional PET for the quantification of myocardial blood flow and coronary flow reserve with 13N-ammonia2015

    • Author(s)
      Masaya Suda, Masahisa Onoguchi, Takeshi Tomiyama
    • Journal Title

      Journal of Nuclear Cardiology

      Volume: 未定 Issue: 3 Pages: 473-474

    • DOI

      10.1007/s12350-015-0098-3

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 心筋および左室容積可変型心臓動態ファントムの開発2015

    • Author(s)
      川村直也,小野口昌久
    • Journal Title

      金沢大学医薬保健学域保健学類放射線技術科学専攻第16回卒業研究論文集

      Volume: 16 Pages: 112-115

    • Related Report
      2014 Research-status Report
    • Acknowledgement Compliant
  • [Presentation] 心筋および左室容積可変型心筋動態ファントムの開発2016

    • Author(s)
      橋本良亮,小野口昌久 ,澁谷孝行 ,原成広,佐藤宗邦
    • Organizer
      第36回日本核医学技術学会総会学術大会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2016-11-03
    • Related Report
      2016 Annual Research Report
  • [Presentation] Comparison between each institution using a 2-Layer double-pump dynamic cardiac phantom2016

    • Author(s)
      Ryosuke Hashimoto, Masahisa Onoguchi, Takayuki Shibutani, Narihiro Hara
    • Organizer
      EANM 2016
    • Place of Presentation
      バルセロナ,スペイン
    • Year and Date
      2016-10-15
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 容積可変型心筋動態ファントムの開発2016

    • Author(s)
      橋本良亮,小野口昌久,澁谷孝行,原 成広,米山寛人,河村昌明
    • Organizer
      第26回日本心臓核医学会総会学術大会
    • Place of Presentation
      アスト津(三重県津市)
    • Year and Date
      2016-07-15
    • Related Report
      2016 Annual Research Report
  • [Presentation] Examination of attenuation correction by using an electrocardiographic synchronized time phase method in myocardial scintigraphy2016

    • Author(s)
      Hara Narihiro, Onoguchi Masahisa, Hojyo Osamu
    • Organizer
      The Society of Nuclear Medicine & Molecular Imaging
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-06-11
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 容積可変型心筋動態ファントムの構築2016

    • Author(s)
      橋本 良亮,小野口 昌久,澁谷 孝行,原 成広,
    • Organizer
      第65回北陸循環器核医学研究会
    • Place of Presentation
      ホテル金沢(石川県金沢市)
    • Year and Date
      2016-02-06
    • Related Report
      2015 Research-status Report
  • [Presentation] 臨床に向けたSPECT/CT 装置の技術検証2015

    • Author(s)
      原 成広
    • Organizer
      日本放射線技術学会核医学部会第20回核医学技術研修会
    • Place of Presentation
      住友病院講堂(大阪府大阪市)
    • Year and Date
      2015-11-22
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 心筋および左室容積可変型心筋動態ファントムの開発2015

    • Author(s)
      橋本良亮,小野口昌久,澁谷孝行,原 成広
    • Organizer
      第55回日本核医学会学術総会
    • Place of Presentation
      ハイアットリージェンシー東京(東京都新宿区)
    • Year and Date
      2015-11-05
    • Related Report
      2015 Research-status Report
  • [Presentation] ダブルポンプを用いた二層構造式の心臓動態ファントムの開発2015

    • Author(s)
      原 成広,小野口 昌久,川口 弘之
    • Organizer
      第43回日本放射線技術学会秋季学術大会
    • Place of Presentation
      金沢市文化ホール(石川県金沢市)
    • Year and Date
      2015-10-08
    • Related Report
      2015 Research-status Report
  • [Presentation] Development of two-layered cardiac dynamic phantom made of special rubber2015

    • Author(s)
      N. Hara, M. Onoguchi, O. Hojyo, Y. Kawaguchi1, M. Murai, F.Udaka, Y. Matsuzawa
    • Organizer
      ICNC12: the International Conference on Nuclear Cardiology and Cardiac CT
    • Place of Presentation
      Congress Centre, Madrid, Spain
    • Year and Date
      2015-05-03 – 2015-05-05
    • Related Report
      2014 Research-status Report
  • [Presentation] Development of Two-layered Cardiac Dynamic Phantom Made of Special Rubber2015

    • Author(s)
      Hara Narihiro, Onoguchi Masahisa, Hojyo Osamu
    • Organizer
      International Conference of Nuclear Cardiology12(ICNC12): Nuclear Cardiology and Cardiac CT
    • Place of Presentation
      Madrid, SPAIN
    • Year and Date
      2015-05-03
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 心筋および左室容積可変型心臓動態ファントムの開発2014

    • Author(s)
      川村直也,小野口昌久
    • Organizer
      金沢大学医薬保健学域保健学類放射線技術科学専攻卒業研究
    • Place of Presentation
      金沢大学(石川県金沢市)
    • Year and Date
      2014-12-19
    • Related Report
      2014 Research-status Report
  • [Remarks] 小野口研究室 業績

    • URL

      http://onoguchi-lab.w3.kanazawa-u.ac.jp/gyouseki.html

    • Related Report
      2016 Annual Research Report
  • [Remarks] 小野口研究室

    • URL

      http://onoguchi-lab.w3.kanazawa-u.ac.jp/index.html

    • Related Report
      2015 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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