| Project/Area Number |
26460730
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical Physics and Radiological Technology
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| Research Institution | Iwate Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
世良 耕一郎 岩手医科大学, 医学部, 教授 (00230855)
小笠原 邦昭 岩手医科大学, 医学部, 教授 (00305989)
米澤 久司 岩手医科大学, 医学部, 准教授 (20240377)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | PET / SUV / 分解能 / 詳細表示 / 脳血流 / アミロイド / 簡略化 |
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| Outline of Final Research Achievements |
The results of the study are as follows. We evaluated the ultimate capability of the PET/CT performance using the PET/CT image reconstruction method. Although the "Japanese guideline for the oncology FDG-PET/CT data acquisition protocol: Synopsis of Version 1.0" targets 10.0-mm tumors to clear the PET/CT images, we found that no fewer than 90% of the 5.0mm diameter in the hot areas indicated SUV 4.0.
Next, to evaluate the study for the brain balance, we scanned for MCI and Alzheimer's disease using PET/CT images. It is often said that amyloid causes brain CBF to decrease. To test this, we fused CBF decrease images into accumulated amyloid images. Then, we drew red on the area of decreased CBF images and blue on the accumulated amyloid images. If the red and blue were in the same area, which turned green, then the result was that the green area was smaller than the red and blue areas. We concluded more pursuit of what has happened in the brain from now on.
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