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Development of diagnostic imaging support system enabling early diagnosis of cerebral infarction by X-ray CT in emergency

Research Project

Project/Area Number 26460732
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical Physics and Radiological Technology
Research InstitutionKitasato University

Principal Investigator

Hara Hidetake  北里大学, 医療衛生学部, 助教 (80381424)

Co-Investigator(Kenkyū-buntansha) 村石 浩  北里大学, 医療衛生学部, 准教授 (00365181)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords脳梗塞 / X線CT / Dual-energy / 逐次近似画像再構成 / 仮想単色画像 / 脳卒中 / 被曝線量 / 画像処理 / 急性期脳梗塞 / Dual-energy CT / 人体ファントム / Dual-Energy CT / Composition image / 救急医療
Outline of Final Research Achievements

In Japan, cerebrovascular disease is the fourth cause of death and the first cause of bedridden patients. This study aimed to develop a method for image-based diagnosis of cerebral infarction, which has been under serious consideration in recent years.
The conditions required to detect acute cerebral infarction by X-ray computed tomography (CT) were examined, and an image-processing algorithm for infarction visualization was developed. The use of Virtual monochromatic imaging in dual-energy CT was evaluated and Adaptive statistical iterative reconstruction images on this visualization. The results demonstrate the possibility of detecting acute cerebral infarction at its early stage, which is difficult to visualize by X-ray CT.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (22 results)

All 2017 2016 2015 2014 Other

All Journal Article (9 results) (of which Peer Reviewed: 6 results,  Acknowledgement Compliant: 9 results) Presentation (11 results) (of which Int'l Joint Research: 4 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] X線CT画像における急性期脳梗塞検出のためのマルチ周波数処理の検討2016

    • Author(s)
      原秀剛,松澤浩紀,阿部慎司,中島康雄
    • Journal Title

      日本保健科学学会誌

      Volume: 19(3) Pages: 140-147

    • NAID

      130007496272

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Composite Images of Dual-Energy CT Aiming at Visualization of Acute Cerebral Stroke in Emergency2016

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Yasuo Nakajima
    • Journal Title

      The Journal of Japan Academy of Health Sciences

      Volume: 19(2) Pages: 92-96

    • NAID

      130007496243

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Dosimetry of Dual-energy CT for the Detection of Acute-Stage Cerebral Infarction : a Phantom Study2016

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Toshiyuki Inoue, Hitoshi Satoh, Shinji Abe, Shinya Mizukami, Tohoru Takeda, Yasuo Nakajima
    • Journal Title

      IEEE NSS/MIC Conference Record

      Volume: 無 Pages: 1-4

    • NAID

      130007728541

    • Related Report
      2016 Annual Research Report
    • Acknowledgement Compliant
  • [Journal Article] Virtual Monochromatic Imaging in Dual-source and Dual-energy CT for Visualization of Acute Ischemic Stroke2015

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Toshiyuki Inoue, Yasuo Nakajima, Hitoshi Satoh, Shinji Abe
    • Journal Title

      J Korean Physical Society

      Volume: 67 Pages: 103-107

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Absorbed Dose Measurement Using Head Dosimetry Phantom for Acute Ischemic Stroke by Dual-energy CT2015

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Toshiyuki Inoue, Hitoshi Satoh, Shinji Abe, Yasuo Nakajima
    • Journal Title

      Asia-Oceania Congress of Medical Physics Proceedings

      Volume: 15 Pages: 96-96

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Visualization of Acute Ischemic Stroke in a Virtual Monochromatic Imaging with Dual-energy CT2015

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Toshiyuki Inoue, Hitoshi Satoh, Shinji Abe, Yasuo Nakajima
    • Journal Title

      International Congress of Radiation Research Late-Breaking Abstract

      Volume: 15 Pages: 10-10

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Possibility to detection of the metastatic brain tumor using dual-source dual-energy CT2015

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Toshiyuki Inoue, Hitoshi Satoh, Shinji Abe, Yasuo Nakajima
    • Journal Title

      Japanese Journal of Medical Physics Proceedings Supplement No.1

      Volume: 35 Pages: 110-110

    • Related Report
      2015 Research-status Report
    • Acknowledgement Compliant
  • [Journal Article] Development of Head Dosimetry Phantom for the Detection of Acute Cerebral Infarction by Dual-energy CT2015

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Toshiyuki Inoue, Hitoshi Satoh, Shinji Abe, Yasuo Nakajima
    • Journal Title

      Japanese Journal of Medical Physics Proceedings Supplement No.3

      Volume: 35 Pages: 159-159

    • Related Report
      2015 Research-status Report
    • Acknowledgement Compliant
  • [Journal Article] Virtual monochromatic imaging in dual-source and dual-energy CT for visualization of acute ischemic stroke2015

    • Author(s)
      Hidetake Hara
    • Journal Title

      The Journal of the Korean Physical Society

      Volume: 5 Pages: 1-9

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Image Quality and Absorbed Dose of Iterative Reconstruction in X-ray CT of Acute Ischemic Stroke2017

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Toshiyuki Inoue, Hitoshi Satoh, Shinji Abe, Yasuo Nakajima
    • Organizer
      European Congress of Radiology 2017
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2017-03-02
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Dosimetry of Dual-energy CT for the Detection of Acute-Stage Cerebral Infarction : a Phantom Study2016

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Toshiyuki Inoue, Hitoshi Satoh, Shinji Abe, Shinya Mizukami, Tohoru Takeda, Yasuo Nakajima
    • Organizer
      IEEE Medical Imaging Conference
    • Place of Presentation
      Strasbourg, France
    • Year and Date
      2016-10-29
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Adaptive Statistical Iterative Reconstruction in X-ray CT for Visualization of Acute Ischemic Stroke2016

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Toshiyuki Inoue, Hitoshi Satoh, Shinji Abe, Yasuo Nakajima
    • Organizer
      The 111th Japan Society of Medical Physics
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2016-04-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] Absorbed Dose Measurement Using Head Dosimetry Phantom for Acute Ischemic Stroke by Dual-energy CT2015

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Toshiyuki Inoue, Hitoshi Satoh, Shinji Abe, Yasuo Nakajima
    • Organizer
      The 15th Asia-Oceania Congress of Medical Physics
    • Place of Presentation
      Kempinski Hotel Xi’an,Xi’an, China
    • Year and Date
      2015-11-05
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Development of Head Dosimetry Phantom for the Detection of Acute Cerebral Infarction by Dual-energy CT2015

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Toshiyuki Inoue, Hitoshi Satoh, Shinji Abe, Yasuo Nakajima
    • Organizer
      第110回日本医学物理学会学術大会
    • Place of Presentation
      北海道大学,北海道札幌市
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
  • [Presentation] Visualization of Acute Ischemic Stroke in a Virtual Monochromatic Imaging with Dual-energy CT2015

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Toshiyuki Inoue, Hitoshi Satoh, Shinji Abe, Yasuo Nakajima
    • Organizer
      The 15th International Congress of Radiation Research
    • Place of Presentation
      京都国際会議場,Kyoto, Japan
    • Year and Date
      2015-05-25
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Possibility to detection of the metastatic brain tumor using dual-source dual-energy CT2015

    • Author(s)
      Hidetake Hara, Hiroshi Muraishi, Hiroki Matsuzawa, Toshiyuki Inoue, Hitoshi Satoh, Shinji Abe, Yasuo Nakajima
    • Organizer
      第109回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜,神奈川県横浜市
    • Year and Date
      2015-04-16
    • Related Report
      2015 Research-status Report
  • [Presentation] Study of non enhancement dual-source dual-energy CT for visualization of metastatic brain tumor : A phantom study2015

    • Author(s)
      Hidetake Hara
    • Organizer
      European Congress of Radiology 2015
    • Place of Presentation
      Vienna (Austria)
    • Year and Date
      2015-03-04 – 2015-03-08
    • Related Report
      2014 Research-status Report
  • [Presentation] Evaluation of dual-source dual-energy CT for visualization of metastatic brain tumor2014

    • Author(s)
      Hidetake Hara
    • Organizer
      14th Asia-Oceania Congress of Medical Physics
    • Place of Presentation
      Hotel Novotel Saigaon (Ho Chi Minh, Vietnam)
    • Year and Date
      2014-10-23 – 2014-10-25
    • Related Report
      2014 Research-status Report
  • [Presentation] Virtual monochlomatic imaging in Dual-source Dual enery CT for Visualization of acute ischemic stroke2014

    • Author(s)
      Hidetake Hara
    • Organizer
      The 7th korea-Japan Meeting on Medical Physics
    • Place of Presentation
      BEXCO (Busan, Korea)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] Study of virtual monochromatic imaging for visualization of acute cerebral infarction in Dual-Energy CT2014

    • Author(s)
      Hidetake Hara
    • Organizer
      The 107th Scientific Meeting of JSMP
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2014-04-10 – 2014-04-13
    • Related Report
      2014 Research-status Report
  • [Remarks] 北里大学研究者情報

    • URL

      http://kerid-web.kitasato-u.ac.jp/Profiles/46/0004551/profile.html

    • Related Report
      2016 Annual Research Report
  • [Patent(Industrial Property Rights)] X線CT装置用ファントム2015

    • Inventor(s)
      原 秀剛
    • Industrial Property Rights Holder
      北里大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-03-23
    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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