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Preparation of polymer gel dosimeters for evaluating a dose for heavy ions

Research Project

Project/Area Number 26460737
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical Physics and Radiological Technology
Research InstitutionNational Institutes for Quantum and Radiological Science and Technology (2016)
Japan Atomic Energy Agency (2014-2015)

Principal Investigator

Hiroki Akihiro  国立研究開発法人量子科学技術研究開発機構, 高崎量子応用研究所 先端機能材料研究部, 主幹研究員(定常) (10370462)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Keywordsポリマーゲル線量計 / 粒子線 / 白濁度合い / ゲル / 放射線架橋 / γ線 / LET / 線量率 / ヒドロキシプロピルセルロース / 炭素線 / 吸光度 / 電子線 / 放射線橋かけ技術
Outline of Final Research Achievements

Polymer gel dosimeters consisting of methacrylate monomers, antioxidant with radiation-crosslinked gel were prepared. The dosimeters became cloudy by exposing to 150 MeV/u He ions, 290 MeV/u C ions, and 500 MeV/u Fe ions. Absorbance of the irradiated dosimeters decreased with increasing dose rate for each ion. The sensitivity of the dosimeters decreased in order of He, C, Fe ions irradiation at the similar dose rate. The increase in a linear energy transfer (LET) affected the decrease in the number of polymerization initiators such as OH radical, resulting in the reduction of the sensitivity of the dosimeters. The sensitivity of the dosimeter was closely correlated with the dose rate and LET. On the other hand, the absorbance of the dosimeter was almost constant along the trajectory of each ion, and then reached a maximum around the Bragg peak. Furthermore, the three-dimensional dose distribution for 290 MeV/u C ions was evaluated by using a multi-layered polymer gel dosimeter.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (14 results)

All 2016 2015 2014

All Journal Article (3 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results,  Acknowledgement Compliant: 3 results) Presentation (11 results) (of which Int'l Joint Research: 2 results,  Invited: 1 results)

  • [Journal Article] Effect of Heavy Ion Irradiation on Optical Property of Radiation-crosslinked Hydroxypropyl Cellulose Gel Containing Methacrylate Monomers2015

    • Author(s)
      A. Hiroki, S. Yamashita, A. Kimura, N. Nagasawa, and M. Taguchi
    • Journal Title

      Nucl. Instr. Meth. Phys. Res. B

      Volume: 365 Pages: 583-586

    • DOI

      10.1016/j.nimb.2015.09.085

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] ヒドロキシプロピルセルロースを用いたゲル線量計の開発2015

    • Author(s)
      廣木 章博
    • Journal Title

      Cellulose Communications

      Volume: 22 Pages: 143-145

    • Related Report
      2015 Research-status Report
    • Acknowledgement Compliant
  • [Journal Article] (1)Enhancement in Dose Sensitivity of Polymer Gel Dosimeters Composed of Radiation-crosslinked Gel Matrix and Less Toxic Monomers.2015

    • Author(s)
      A. Hiroki, S. Yamashita, and M. Taguchi
    • Journal Title

      Journal of Physics: Conference Series

      Volume: 573 Pages: 012028-012028

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 放射線架橋ゲルを母材とするポリマーゲル線量計材料の高感度化2016

    • Author(s)
      廣木章博、小曽根雄介、山下真一、木村敦、長澤尚胤、田口光正
    • Organizer
      第5回3Dゲル線量計研究会
    • Place of Presentation
      京大宇治キャンパス(京都府・宇治市)
    • Year and Date
      2016-12-03
    • Related Report
      2016 Annual Research Report
  • [Presentation] 電子線架橋ヒドロキシプロピルセルロースゲルを用いて作製した ポリマーゲル線量計材料の高感度化2016

    • Author(s)
      廣木章博、小曽根雄介、山下真一、木村敦、長澤尚胤、田口光正、村上健
    • Organizer
      第59回放射線化学討論会
    • Place of Presentation
      高崎量子応用研究所(群馬県・高崎市)
    • Year and Date
      2016-09-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] 放射線感受性ゲル材料の線量応答に及ぼす線質の影響2015

    • Author(s)
      廣木章博、山下真一、木村敦、長澤尚胤、田口光正
    • Organizer
      日本化学会関東支部群馬地区研究交流発表会
    • Place of Presentation
      群馬工業高等専門学校 大会議室(群馬県前橋市)
    • Year and Date
      2015-12-05
    • Related Report
      2015 Research-status Report
  • [Presentation] 放射線感受性ゲルシートの積層による3次元線量分布評価の試み2015

    • Author(s)
      廣木章博、山下真一、木村敦、長澤尚胤、村上健、田口光正
    • Organizer
      第110回医学物理学会学術大会
    • Place of Presentation
      北海道大学 学友会館フラテ(北海道札幌市)
    • Year and Date
      2015-09-19
    • Related Report
      2015 Research-status Report
  • [Presentation] ヒドロキシプロピルセルロースを用いたゲル線量計の開発2015

    • Author(s)
      廣木章博
    • Organizer
      セルロース学会関東支部ミニシンポジウム
    • Place of Presentation
      東京大学 中島董一郎記念ホール(東京都文京区)
    • Year and Date
      2015-09-04
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] Dose response of polymer gel dosimeter based on hydroxypropyl cellulose hydrogel ~ Toward the application on heavy ion therapy ~2015

    • Author(s)
      A. Hiroki, S. Yamashita, A. Kimura, N. Nagasawa, and M. Taguchi
    • Organizer
      15th International Congress of Radiation Research
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Year and Date
      2015-05-25
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effect of heavy ion irradiation on optical property of radiation-crosslinked hydroxypropyl cellulose gel containing methacrylate monomers2015

    • Author(s)
      A. Hiroki, S. Yamashita, A. Kimura, N. Nagasawa, and M. Taguchi
    • Organizer
      Swift Heavy ions in Matter 2015
    • Place of Presentation
      Darmstadt, Germany
    • Year and Date
      2015-05-18
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 放射線橋かけ技術を用いて作製したポリマーゲル線量計~重粒子線に対する応答性を吸光度及び画像データから評価する~2014

    • Author(s)
      廣木章博、山下真一、田口光正、村上健
    • Organizer
      第3回3Dゲル線量計研究会
    • Place of Presentation
      名古屋大学 野依記念学術交流館(愛知県名古屋市)
    • Year and Date
      2014-11-23
    • Related Report
      2014 Research-status Report
  • [Presentation] LET Dependence on the Dose Response of the Polymer Gel Dosimeter Based on Radiation-crosslinked Hydroxypropyl Cellulose Gel2014

    • Author(s)
      Hiroki A., Yamashita S., Kimura A., Nagasawa N., Taguchi M.
    • Organizer
      5th Asia Pacific Symposium on Radiation Chemistry 2014
    • Place of Presentation
      東京大学 弥生キャンパス 弥生講堂(東京都文京区)
    • Year and Date
      2014-09-09
    • Related Report
      2014 Research-status Report
  • [Presentation] Enhancement in dose sensitivity of polymer gel dosimeters composed of radiation-crosslinked gel matrix and less toxic monomers2014

    • Author(s)
      Hiroki A., Yamashita S., Taguchi M.
    • Organizer
      8th International Conference on 3D Radiation Dosimetry
    • Place of Presentation
      Ystad Saltsjobad (Ystad, Sweden)
    • Year and Date
      2014-09-07
    • Related Report
      2014 Research-status Report
  • [Presentation] 重粒子線に対する新規ポリマーゲル線量計の線量応答性2014

    • Author(s)
      廣木章博、山下真一、木村敦、長澤尚胤、田口光正、村上健
    • Organizer
      第107回日本医学物理学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-04-12
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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