| Project/Area Number |
26460752
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Osaka City University |
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Principal Investigator |
SATO KYOKO 大阪市立大学, 大学院医学研究科, 准教授 (00381989)
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| Co-Investigator(Kenkyū-buntansha) |
林 朝茂 大阪市立大学, 大学院医学研究科, 教授 (10381980)
圓藤 吟史 大阪市立大学, 大学院医学研究科, 教授 (20160393)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | 疫学 / 脂肪酸 / 生活習慣病 |
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| Outline of Final Research Achievements |
In the prospective cohort study to examine the association between visceral adiposity measured by computed tomography (CT) and lifestyle-related diseases, we measured baseline fatty acid composition of serum lipids.
We cross-sectionally examined the association between baseline fatty acid composition of serum lipids and the prevalence of lifestyle-related diseases or body fat distribution using multivariate analyses. The elevated palmitic acid level was associated with the high prevalence of diabetes. Among men, the elevated dihomo-γ-linolenic acid level was positively associated with abdominal subcutaneous fat area and intra-abdominal fat area. We prospectively examined the association between baseline fatty acid composition of serum lipids and the incidence of lifestyle-related diseases using multivariate analyses. The elevated oleic acid level at baseline was positively associated with the incidence of diabetes.
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