| Project/Area Number |
26460768
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Ehime University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
廣岡 昌史 愛媛大学, 医学部附属病院, 准教授 (30432785)
日浅 陽一 愛媛大学, 医学系研究科, 教授 (70314961)
谷川 武 順天堂大学, 医学(系)研究科(研究院), 教授 (80227214)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 肝疾患 / 睡眠呼吸障害 / 肝細胞癌 / 睡眠時無呼吸症候群 / 肝細胞ガン / 発がん / 睡眠時間 |
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| Outline of Final Research Achievements |
85 patients with hepatocellular cancer were enrolled in this study (69 male patients, 53 -83 years). A self-administered questionnaire was used to assess Pittsburgh Sleep Quality Index, Epworth Sleepness Scale, nocturia, drinking habits, smoking habits, eating habits, and exercise habits. The stage of hepatocellular cancer, and liver function was collected based on medical record.
The assessment of sleep-disordered breathing (SDB): A pulse oximeter (PULSOX 3Si; Minolta Co., Osaka, Japan) was attached to the left wrist. The severity of sleep breathing disorder was defined by the 3% oxygen desaturation index level: normal, less than five events per hour; SDB, 5 or more; events per hour; moderate to severe SBD 15 or more; events per hour. We would estimate the association between the severity of SBD and prognosis of hepatocellular cancer after data cleaning.
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