New method for aiding detection of abnormal thyroid function in patients making use of set of routine tests – applying it in screening during general health check-ups or visiting hospitals
| Project/Area Number |
26460777
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Tohoku Medical and Pharmaceutical University |
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Principal Investigator |
SATO Kenichi 東北医科薬科大学, 薬学部, 教授 (30158935)
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| Co-Investigator(Kenkyū-buntansha) |
川上 準子 東北医科薬科大学, 薬学部, 講師 (40438560)
星 憲司 東北医科薬科大学, 薬学部, 講師 (20405913)
青木 空眞 東北医科薬科大学, 薬学部, 助教 (40584462)
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| Research Collaborator |
YOSHIDA Katsumi 東北公済病院, 医学管理センター, 医師
MORI Kouki JR仙台病院, 健康管理センター長
NAKAGAWA Yoshinori 仙台甲状腺クリニック, 院長
YAMAGISHI Toshio 東北公済病院, 内科部長
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 甲状腺機能異常 / 基本的検査 / スクリーニング / 時系列データ / パターン認識手法 / 人工知能 / 健診・外来 / インフォマティクス / 診断支援 |
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| Outline of Final Research Achievements |
We developed a new simple, low-cost method for detecting patients with overt thyroid dysfunction (PTD) using the combination of six routine tests already measured without measuring thyroid hormone. The existing procedure comprised 6 routine tests (alkaline phosphatase (ALP), serum creatinine (S-Cr), total cholesterol (TC), heart rate (HR), lactate dehydrogenase (LDH) and red blood cell (RBC)). We performed this screening for many participants more than 20000 attending health-checkup at Ningen Docks in JR Sendai Hospital and Tohoku Kousai Hospital, and found more than 40 PTDs, most of them was suspected of thyroid dysfunction by a medical examination. Furthermore, it was found that a very highly-detailed prediction not to be affected by the individual difference was possible when there was the value last time.
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Report
(4 results)
Research Products
(31 results)
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[Journal Article] Assisting the diagnosis of Cushing syndrome by pattern recognition methods, using a combination of eight routine tests and their multiple correlation with serum cortisol2014
Author(s)
Masataka Kudo, Fumitoshi Satoh, Sorama Aoki, Ryo Morimoto, Yoshitsugu Iwakura, Yoshikiyo Ono, Ken Matsuda, Akira Sugawara, Katsumi Yoshida, Kenichi Sato, Sadayoshi
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Journal Title
Biomedicine & Aging Pathology
Volume: 4
Issue: 3
Pages: 257-264
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Presentation] Analyzing data of steroid replacement therapy after surgery for Cushing's syndrome by using the pattern recognition methods and mathematical modelling to assist appropriate steroid supplement2014
Author(s)
Kenichi Sato , Masataka Kudo a, Fumitoshi Satoh a, Sorama Aoki, Ryo Morimoto a, Yoshitsugu Iwakura a, Yoshikiyo Ono a, Ken Matsuda a, Akira Sugawara a, Katsumi Yoshida b, and Sadayoshi Ito a
Organizer
The 2014 International Conference on Brain Informatics and Health
Place of Presentation
Warsaw (Poland)
Year and Date
2014-08-12
Related Report
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