Study on prevalence and molecular epidemiological characteristics of novel community-acquired MRSA that emerged in Japan
| Project/Area Number |
26460804
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Hygiene and public health
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
鷲見 紋子 札幌医科大学, 医学部, 准教授 (10363699)
漆原 範子 札幌医科大学, 医学部, 准教授 (80396308)
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| Research Collaborator |
KAWAGUCHIYA Mitsuyo
AUNG Meijisoe
ITO Masahiko
SHINAGAWA Masaaki
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | メチシリン耐性黄色ブドウ球菌 / ACME / SCCmec-IVl / 北海道 / MRSA / 分子疫学 / 市中感染 / ST / ＭＲＳＡ / ＡＣＭＥ / ＳＴ |
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| Outline of Final Research Achievements |
Methicillin-resistant Staphylococcus aureus (MRSA) is drug-resistant bacteria known for a long time. Recently, two MRSA clones with novel genetic traits (①MRSA harboring SCCmec-IVl which is a novel genetic complex; ②Coagulase type-II MRSA having ACME which is a genetic complex related to attachment to human skin) have been reported. We investigated their prevalence in clinical isolates in Hokkaido, Japan. These MRSA ①, ② were detected in 3.5% and 5.1% of isolates from outpatients of community, and 3% and 0.9% of isolates from a university hospital, respectively. Genetic diversity was found in MRSA with ACME, and their spread in the community and hospitals was concerned.
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Report
(5 results)
Research Products
(26 results)
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[Journal Article] A Colonization Outbreak of Penicillin-Susceptible mecA-Positive Staphylococcus aureus in a Neonatal Ward of Children's Hospital.2018
Author(s)
Minami K, Terakawa R, Sato M, Shoji Y, Hiroma T, Nakamura T, Horiuchi A, Otsuka A, Kubota N, Hidaka E, Kawakami Y, Aung MS, Kobayashi N
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Journal Title
Infect Control Hosp Epidemiol.
Volume: 39
Issue: 2
Pages: 239-241
DOI
Related Report
Peer Reviewed
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[Journal Article] Prevalence and Genetic Characteristics of Staphylococcus aureus and Staphylococcus argenteus Isolates Harboring Panton-Valentine Leukocidin, Enterotoxins, and TSST-1 Genes from Food Handlers in Myanmar.2017
Author(s)
Aung MS, San T, Aye MM, Mya S, Maw WW, Zan KN, Htut WHW, Kawaguchiya M, Urushibara N, Kobayashi N
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Journal Title
Toxins
Volume: 9
Issue: 8
Pages: 241-253
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Drug resistance and genetic characteristics of clinical isolates of staphylococci in Myanmar : high prevalence of PVL among methicillin-susceptible Staphylococcus aureus belonging to various sequence types.2016
Author(s)
Aung MS, Zi H, New KM, Maw WW, Aung MT, Min WW, Nyein N, Kawaguchiya M, Urushibara N, Sumi A, Kobayashi N
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Journal Title
New Microbes and New Infections
Volume: 10
Pages: 58-65
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] High prevalence of blaOXA-23 in Acinetobacter spp. and detection of blaNDM-1 in A. soli in Cuba: Report from National Surveillance Program (2010-2012).2015
Author(s)
Quiñones D, Carvajal I, Perez Y, Hart M, Perez J, Garcia S, Salazar D, Ghosh S, Kawaguchiya M, Aung MS, Kobayashi N
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Journal Title
New Microbes and New Infections
Volume: 7
Pages: 52-56
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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