Assessment of the Effect of health for infants by TBBPA and their metabolites as an indicator of the steroid hormones
| Project/Area Number |
26460814
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Hygiene and public health
|
|---|
| Research Institution | Setsunan University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | Flame retardant / TBBPA / Sex hormone / 臭素化難燃剤 / 残留性有機汚染物質 / TeBBPA / GC-MS / 性ホルモン / BPA / TriBBPA / DiBBPA / MoBBPA |
|---|
| Outline of Final Research Achievements |
I succeeded in elucidation of TBBPA contamination level in infant food, and in variation of monitoring method of the sex steroid hormones using GC/MS. I investigated the contamination level of foods and breast milk for infants, TBBPA level in breast milk was higher than that of infant foods. Interestingly, the breast milk was detected to metabolites as tribromobisphenol A. From these results, I pointed out importance of monitoring to metabolites such as debrominated TBBPA. Moreover, I enabled to confirm for monitoring method of sex steroid hormones (four kinds of androgens, three kinds of estrogens, three kinds of progestins and metabolites).
|
Report
(4 results)
Research Products
(27 results)
-
[Journal Article] Levels of tetrabromobisphenol A, tribromobisphenol A, dibromobisphenol A, monobromobisphenol A, and bisphenol A in Japanese breast milk.2015
Author(s)
Nakao, T., Akiyama, E., Kakutani, H., Mizuno, A., Aozasa, O., Akai, Y., Ohta, S.
-
Journal Title
Chemical Research in Toxicology
Volume: 28
Issue: 4
Pages: 722-728
DOI
Related Report
Peer Reviewed
-
[Journal Article] <b>Detection of Tribromobisphenol A as Debrominated Compounds of </b><b>Tetrabromobisphenol A in Breast Milk Collected in Japan </b>2015
Author(s)
Nakao, T., Akiyama, E., Kakutani, H., Mizuno, A., Aozasa, O., Akai, Y., Ohta, S.
-
Journal Title
Journal of Environmental Chemistry
Volume: 25
Issue: 2
Pages: 69-77
DOI
NAID
ISSN
0917-2408, 1882-5818
Related Report
Peer Reviewed
-
[Journal Article] Facilitation of adipocyte differentiation of 3T3-L1 cells by debrominated tetrabromobisphenol A compounds detected in Japanese breast milk2015
Author(s)
Akiyama, E., Kakutani, H., Nakao, T., Motomura, Y., Takano, Y., Sorakubo, R., Mizuno, A., Aozasa, O., Tachibana, K., Doi, T., Ohta, S.
-
Journal Title
Environmenta Research
Volume: 140
Pages: 157-164
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
