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Economic Evaluation of Immunisation Programme of PPSV-23 and the Inclusion of PCV-13 in the List for Single-Dose Subsidy to the Elderly in Japan.

Research Project

Project/Area Number 26460824
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Hygiene and public health
Research InstitutionUniversity of Tsukuba

Principal Investigator

OKUBO Ichiro  筑波大学, 医学医療系, 教授 (40323307)

Co-Investigator(Kenkyū-buntansha) 星 淑玲  筑波大学, 医学医療系, 研究員 (90506320)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords予防接種 / ワクチン / 肺炎球菌 / 費用効果分析 / 費用効用分析 / 経済評価
Outline of Final Research Achievements

We performed economic evaluations to investigate the efficiency of inclusion of PCV-13 in the list for single-dose pneumococcal vaccine immunisation programme. We constructed a Markov model depicting the S.pneumoniae-related disease course pathways. Cost of per shot of vaccine was \8,116 for PPSV-23 and \10,776 for PCV-13.
Compared to current PPSV-23 strategy, PCV-13 inclusion into the list for single-dose pneumococcal vaccine immunization programme has an ICER of \379,000 per QALY gained regardless of the PCV-13 diffusion level. This ICERs were found to be cost-effective since they are lower than the suggested criterion by WHO of three times GDP.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (2 results)

All 2015

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (1 results)

  • [Journal Article] Economic Evaluation of Immunisation Programme of 23-Valent Pneumococcal Polysaccharide Vaccine and the Inclusion of 13-Valent Pneumococcal Conjugate Vaccine in the List for Single-Dose Subsidy to the Elderly in Japan.2015

    • Author(s)
      Hoshi SL, Kondo M, Okubo I.
    • Journal Title

      PLoS One.

      Volume: 10(10): Issue: 10 Pages: e0139140-e0139140

    • DOI

      10.1371/journal.pone.0139140

    • NAID

      120007135935

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] ECONOMIC EVALUATION OF PPSV-23 VACCINATION PROGRAMME AND PCV-13 INCLUSION IN THE LIST FOR SINGLE-DOSE SUBSIDY TO THE ELDERLY IN JAPAN2015

    • Author(s)
      星淑玲・近藤正英・大久保一郎
    • Organizer
      The 5th Asian Vaccine Conference (ASVAC 2015)
    • Place of Presentation
      ハノイ(ベトナム)
    • Year and Date
      2015-06-12 – 2015-06-14
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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