Construction of support system for siblings with ASD based on medical evaluation

• Project/Area Number: 26460829
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Hygiene and public health
• Research Institution: University of Fukui
• Principal Investigator: Kawatani Masao 福井大学, 学術研究院医学系部門(附属病院部), 講師 (10362047)
• Co-Investigator(Kenkyū-buntansha): 高橋 哲也 福井大学, 保健管理センター, 准教授 (00377459)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 脳波 / 非線形解析 / 自閉スペクトラム症 / 注意欠如・多動症 / 同胞 / きょうだい支援 / 自閉症スペクトラム障害 / 注意欠陥多動性障害

Outline of Final Research Achievements

We have clarified the diversity of clinical characterisitcs in the case of siblings of neurodevelopmental disorders including ASD. We also established a method to evaluate the complexity of EEG using nonlinear analysis and graph analysis and clarified that it is useful as a method for objectively evaluating the diagnosis and pathology of neurodevelopmental disorder in children. In addition, we have constructed sibling support system based on these medical evaluations, and have practiced support activities according to individual characteristics and needs.

Research Products

• [Journal Article] Decision making processes based on social conventional rules in early adolescents with and without autism spectrum disorders. (2016)
  • Author(s): Komeda, H., Osanai, H., Yanaoka, K., Okamoto, Y., Fujioka, T., Arai, S., Inohara, K., Koyasu, M., Kusumi, T., Takiguchi, S., Kawatani, M., Kumazaki, H., Hiratani, M., Tomoda, A., & Kosaka, H.
  • Journal Title: Scientific Reports Volume: 6 Issue: 1 Pages: 37875-37875
  • DOI: 10.1038/srep37875
  • NAID: 120005890337
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Enhanced brain signal variability in children with autism spectrum disorder during early childhood. (2016)
  • Author(s): Takahashi T, Yoshimura Y, Hiraishi H, Hasegawa C, Munesue T, Higashida H, Minabe Y, Kikuchi M.
  • Journal Title: Hum Brain Mapp. Volume: 37（3） Issue: 3 Pages: 1038-1050
  • DOI: 10.1002/hbm.23089
  • Peer Reviewed / Open Access
• [Journal Article] Changes in EEG complexity with electroconvulsive therapy in a patient with autism spectrum disorders: a multiscale entropy approach. (2015)
  • Author(s): Okazaki R, Takahashi T*, Ueno K, Takahashi, Ishitobi M, Kikuchi M, Higashima M, Wada Y.
  • Journal Title: Front Hum Neurosci Volume: ９ Pages: 17-17
  • DOI: 10.3389/fnhum.2015.00106
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Neurophysiological basis of creativity in healthy elderly people: a multiscale entropy approach. (2015)
  • Author(s): Ueno K, Takahashi T, Takahashi K, Mizukami K, Tanaka Y, Wasa Y.
  • Journal Title: Clinical Neurophysiology Volume: 126 Issue: 3 Pages: 524-531
  • DOI: 10.1016/j.clinph.2014.06.032
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Presentation] 「福井県における自閉症児のきょうだい支援の実際と課題」 ～小児科医、きょうだいの立場より～ (2017)
  • Author(s): 川谷正男
  • Organizer: 第59回日本小児神経学会総会
  • Place of Presentation: 大阪国際会議場（大阪府大阪市）
  • Year and Date: 2017-06-15
• [Presentation] Clinical diversity in siblings with developmental dyslexia (2017)
  • Author(s): Masao Kawatani, Takuya Kosaka, Genrei Ohta, Hiroshi Kometani, Shinichiro Takiguchi, Yusei Ohshima, Akemi Tomoda, Michio Hiratani
  • Organizer: 14th Asian and Oceanian Congress of Child Neurology (AOCCN2017)
  • Place of Presentation: Hilton Fukuoka Sea Hawk (Fukuoka, Japan）
  • Year and Date: 2017-05-11
  • Int'l Joint Research
• [Presentation] ネットワーク解析を用いたてんかん性発射を有する神経発達障害の脳波特徴 (2016)
  • Author(s): 川谷 正男, 巨田 元礼, 岡崎 玲子, 大嶋 勇成, 平谷 美智夫, 高橋 哲也
  • Organizer: 第50回日本てんかん学会学術集会
  • Place of Presentation: グランシップ（静岡県静岡市）
  • Year and Date: 2016-10-07
• [Presentation] 発達性ディスレクシアの同胞例における臨床的多様性 (2016)
  • Author(s): 川谷 正男, 巨田 元礼, 米谷 博, 滝口 慎一郎, 大嶋 勇成, 友田 明美, 平谷 美智夫
  • Organizer: 第58回日本小児神経学会総会
  • Place of Presentation: 京王プラザホテル新宿（東京都新宿区）
  • Year and Date: 2016-06-02
• [Presentation] 幼児期より療育を受け、就学後に発達性読字障害と診断された症例の臨床的特徴の検討 (2016)
  • Author(s): 巨田 元礼, 川谷 正男, 滝口 慎一郎, 米谷 博, 平谷 美智夫, 大嶋 勇成
  • Organizer: 第58回日本小児神経学会総会
  • Place of Presentation: 京王プラザホテル新宿（東京都新宿区）
  • Year and Date: 2016-06-02
• [Presentation] 発達障害の双胎例における臨床的多様性 (2015)
  • Author(s): 川谷正男、巨田元礼 、米谷博 、大嶋勇成、友田明美、平谷美智夫
  • Organizer: 第57回日本小児神経学会学術集会
  • Place of Presentation: 大阪
  • Year and Date: 2015-05-28
• [Presentation] Neural network mechanism for siblings with neurodevelopmental disorders using non-linear analytic methods (2015)
  • Author(s): Kawatani M, Takahashi T, Ohta G, Kometani H, Ohshima Y, Tomoda A, Hiratani M
  • Organizer: AOCCN2015
  • Place of Presentation: 台北（台湾）
  • Year and Date: 2015-05-14
  • Int'l Joint Research
• [Presentation] 発達障害の同胞例における非線形解析を用いた脳波研究 (2014)
  • Author(s): 川谷正男、高橋哲也、巨田元礼 、米谷博 、大嶋勇成、友田明美、平谷美智夫
  • Organizer: 第56回日本小児神経学会
  • Place of Presentation: アクトシティ浜松（静岡県浜松市）
  • Year and Date: 2014-05-29 – 2014-05-31
• [Book] 発達障害の疑問に答える （保護者やきょうだいへの支援はどうあるべきでしょうか？） (2015)
  • Author(s): 黒木俊秀（編著）、川谷正男（共著）
  • Total Pages: 200
  • Publisher: 慶應義塾大学出版会