Risk of visceral fat accumulation in young adulthood

• Project/Area Number: 26460837
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Hygiene and public health
• Research Institution: Nagasaki University
• Principal Investigator: YAMASAKI Hironori 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員 (40346953)
• Co-Investigator(Kenkyū-buntansha): 田山 淳 長崎大学, 教育学部, 准教授 (10468324) ; 前田 隆浩 長崎大学, 医歯薬学総合研究科(医学系), 教授 (40284674) ; 高村 昇 長崎大学, 原爆後障害医療研究所, 教授 (30295068) ; 古林 正和 長崎大学, 保健・医療推進センター, 准教授 (00380874) ; 調 漸 長崎大学, 保健・医療推進センター, 教授 (40264220)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2014: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 内臓脂肪 / 若年成人 / 高血圧 / 血圧 / メタボリックシンドローム / 内臓脂肪面積

Outline of Final Research Achievements

A relationship between hypertension and intra-abdominal fat (IAF) in young adulthood is not clear. In a cross-sectional study, intra-abdominal fat area was measured using a dual bioelectrical impedance analysis instrument in 697 university students (20.3±0.7 years, 425 men). Blood pressure and anthropometric factors were measured. Lifestyle variables including smoking, drinking, physical activity, and eating behavior were assessed with questionnaire. High blood pressure risk (SBP>-130mm Hg and/or DBP>-85mm Hg) with increasing IAF area was evaluated. Participants were divided into 5 groups according to their intra-abdominal fat area (-24.9, 25.0-49.9, 50-74.9, 75-99.9, and 100- cm2). As compared with the values of the smallest IAF area group, the lifestyle-adjusted odds ratios (ORs) were elevated (OR 1.31, 95% CI 0.66-2.80; OR 3.38, 95% CI 1.60-7.57; OR 7.71, 95% CI 2.75-22.22; OR 18.74, 95% CI 3.93-105.64, respectively). The risk increase was observed only in men.

Research Products

• [Journal Article] Intra-abdominal fat accumulation is a hypertension risk factor in young adulthood: A cross-sectional study (2016)
  • Author(s): Takeoka A, Tayama J, Yamasaki H, Kobayashi M, Ogawa S, Saigo T, Kawano H, Abiru N, Hayashida M, Maeda T, Shirabe S
  • Journal Title: Medicine (Baltimore) Volume: 95 Issue: 45 Pages: e5361-e5361
  • DOI: 10.1097/md.0000000000005361
  • NAID: 120006987609
  • Peer Reviewed / Open Access
• [Journal Article] Impact of Helicobacter pylori Immunoglobulin G Levels and Atrophic Gastritis Status on Risk of Metabolic Syndrome (2016)
  • Author(s): Takeoka A, Tayama J, Yamasaki H, Kobayashi M, Ogawa S, Saigo T, Hayashida M, Shirabe S
  • Journal Title: PLoS One Volume: 11 Issue: 11 Pages: e0166588-e0166588
  • DOI: 10.1371/journal.pone.0166588
  • Peer Reviewed / Open Access
• [Presentation] 若年成人における内臓脂肪と血圧の関連性についての検討 (2015)
  • Author(s): 山崎浩則，武岡敦之，田山淳，阿比留教生，調 漸
  • Organizer: デュアルインピーダンス法を用いた内臓脂肪測定法研究会
  • Place of Presentation: 京都市
  • Year and Date: 2015-09-05