Construction of infection control support system using leukocytes differential scattergram pattern of CBC

• Project/Area Number: 26460865
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Medical and hospital managemen
• Research Institution: Kawasaki University of Medical Welfare (2016); Kochi University (2014-2015)
• Principal Investigator: Kataoka Hiromi 川崎医療福祉大学, 医療福祉マネジメント学部, 教授 (80398049)
• Co-Investigator(Kenkyū-buntansha): 奥原 義保 高知大学, 教育研究部医療学系連携医学部門, 教授 (40233473) ; 杉浦 哲朗 高知大学, 医学部附属病院, 特任教授 (50171145) ; 久原 太助 高知大学, 医学部附属病院, 臨床検査技師 (80457407)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2014: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
• Keywords: CBC / スキャッタグラム / MRSA / 抗生剤治療 / インフルエンザ / パンデミック / 抗生剤 / 迅速効果判定 / CBCスキャッターグラム / 投薬クールイベント / データウエアハウス

Outline of Final Research Achievements

'Rapid post-antibiotic effect assessment by leukocytes differential scattergram in patients with MRSA infection': The variations of scattergram patterns were useful to evaluate the effects of antibiotic therapy early as one day after the administration in patients with MRSA infection.
'Pre-detection of pandemic outbreak of influenza using leukocytes differential scattergram obtained by CBC': We evaluated leukocytes differential scattergram pattern of the white blood cells obtained by commonly performed CBC and applied the results to detect outbreak of influenza using the big data of non-onset population. This study indicated that patients vulnerable to influenza infection could be classified by the leukocytes differential scattergram pattern. Moreover, effective preventive measures against infection could be done by pre-detection of leukocytes differential scattergram pattern in a non-onset population.

Research Products

• [Journal Article] CBC検査の白血球粒度分布パターンを用いたインフルエンザパンデミック (2016)
  • Author(s): 片岡浩巳, 久原太助, 畠山豊, 奥原義保, 松村敬久, 杉浦哲朗
  • Journal Title: 医療情報学 Volume: 36 Pages: 738-741
  • Peer Reviewed
• [Journal Article] MRSA感染症における白血球粒度パターンを用いた抗生剤迅速効果判定法 (2015)
  • Author(s): 片岡浩巳,畠山 豊,奥原 義保,久原 太助,松村 敬久,杉浦 哲朗
  • Journal Title: 医療情報学 Volume: 35 Pages: 680-683
  • Peer Reviewed
• [Presentation] CBC検査の白血球粒度分布パターンを用いたインフルエンザパンデミックの事前検知 (2016)
  • Author(s): 片岡浩巳, 久原太助, 畠山豊, 奥原義保, 松村敬久, 杉浦哲朗
  • Organizer: 第36回医療情報学連合大会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2016-11-24
• [Presentation] Big Data Analysis in Clinical Laboratories (2016)
  • Author(s): Hiromi Kataoka
  • Organizer: The 10th International Conference of Clinical Laboratory Automation (Cherry Blossom Symposium2016)
  • Place of Presentation: GLAD Hotel Yeouido(Seoul, Korea)
  • Year and Date: 2016-04-22
  • Int'l Joint Research / Invited
• [Presentation] MRSA感染症における白血球粒度パターンを用いた抗生剤迅速効果判定法 (2015)
  • Author(s): 片岡浩巳,畠山 豊,奥原 義保,久原 太助,松村 敬久,杉浦 哲朗
  • Organizer: 第35回医療情報学連合大会
  • Place of Presentation: 沖縄コンベンションセンター（沖縄県）
  • Year and Date: 2015-11-01
• [Presentation] Rapid evaluation of post-antibiotic effects by leukocytes differential scattergram (2015)
  • Author(s): H. Kataoka, Y. Ochi, Y. Hatakeyama, Y. Okuhara, T. Hisahara, Y. Matsumura, T. Sugiura
  • Organizer: ISLH2015
  • Place of Presentation: Chicago, USA
  • Year and Date: 2015-05-19
  • Int'l Joint Research
• [Presentation] 白血球粒度パターンを用いた抗生剤迅速効果判定法 (2014)
  • Author(s): 片岡 浩巳、越智 康浩、畠山 豊、奥原 義保、久原 太助、松村 敬久、杉浦 哲朗
  • Organizer: 第61回日本臨床検査医学会学術集会
  • Place of Presentation: 福岡（福岡国際会議場）
  • Year and Date: 2014-11-22 – 2014-11-25
• [Presentation] 動的クールイベント検出法の開発とその適用事例の性能評価 (2014)
  • Author(s): 片岡 浩巳 畠山 豊 奥原 義保
  • Organizer: 第34回医療情報学連合大会
  • Place of Presentation: 千葉（幕張メッセ国際会議場）
  • Year and Date: 2014-11-06 – 2014-11-08