ChinesePlex: A method for differentiation of Japanese and Chinese using Chinese-specific alleles
Project/Area Number |
26460878
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Legal medicine
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Research Institution | Tottori University |
Principal Investigator |
Yuasa Isao 鳥取大学, 医学部, 特任教授 (00093633)
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Co-Investigator(Renkei-kenkyūsha) |
AKANE Atsushi 関西医科大学, 医学部, 教授 (70202520)
ISHIKAWA Takaki 大阪市立大学, 医学部, 教授 (50381984)
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Project Period (FY) |
2014-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 中国人 / 日本人 / 特異遺伝子 / 個人識別 / PCR / DNA解析 |
Outline of Final Research Achievements |
To find out Chinese-specific alleles, 282 candidate SNPs chosen from the 1000 genomes database were investigated in 875 DNA samples from nine East Asian, African, and European populations. Of 177 amplified SNPs showing polymorphisms, 160 derived alleles were detected in Japanese populations. The remaining 17 alleles were observed not only in Chinese but also in other East Asians except for Japanese, indicating the derived alleles were Continent-specific alleles. Because they are not adequate for demonstration that a forensic sample came from a Chinese, they were incorporated into JapanesePlex single base extension method.
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Report
(4 results)
Research Products
(19 results)
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[Journal Article] Epileptic phenotype of FGFR3-related bilateral medial temporal lobe dysgenesis.2017
Author(s)
Tetsuya Okazaki, Yoshiaki Saito, Riyo Ueda, Takeya Awashima, Yoko Nishimura, Isao Yuasa, Yuki Shinohara, Kaori Adachi, Masayuki Sasaki, Eiji Nanba, Yoshihiro Maegeki:
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Journal Title
Brain and Development
Volume: 39
Issue: 1
Pages: 67-71
DOI
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Peer Reviewed
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[Presentation] 中国人特異的アレルの検出2016
Author(s)
松末 綾、梅津和夫、飯野守男、湯浅 勲:
Organizer
第25回日本DNA多型学会学術集会
Place of Presentation
東京大学大気海洋研究所(千葉県柏市)
Year and Date
2016-11-30
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