• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

ChinesePlex: A method for differentiation of Japanese and Chinese using Chinese-specific alleles

Research Project

Project/Area Number 26460878
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Legal medicine
Research InstitutionTottori University

Principal Investigator

Yuasa Isao  鳥取大学, 医学部, 特任教授 (00093633)

Co-Investigator(Renkei-kenkyūsha) AKANE Atsushi  関西医科大学, 医学部, 教授 (70202520)
ISHIKAWA Takaki  大阪市立大学, 医学部, 教授 (50381984)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords中国人 / 日本人 / 特異遺伝子 / 個人識別 / PCR / DNA解析
Outline of Final Research Achievements

To find out Chinese-specific alleles, 282 candidate SNPs chosen from the 1000 genomes database were investigated in 875 DNA samples from nine East Asian, African, and European populations. Of 177 amplified SNPs showing polymorphisms, 160 derived alleles were detected in Japanese populations. The remaining 17 alleles were observed not only in Chinese but also in other East Asians except for Japanese, indicating the derived alleles were Continent-specific alleles. Because they are not adequate for demonstration that a forensic sample came from a Chinese, they were incorporated into JapanesePlex single base extension method.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (19 results)

All 2017 2016 2015 2014

All Journal Article (11 results) (of which Peer Reviewed: 11 results,  Open Access: 4 results,  Acknowledgement Compliant: 5 results) Presentation (8 results)

  • [Journal Article] Epileptic phenotype of FGFR3-related bilateral medial temporal lobe dysgenesis.2017

    • Author(s)
      Tetsuya Okazaki, Yoshiaki Saito, Riyo Ueda, Takeya Awashima, Yoko Nishimura, Isao Yuasa, Yuki Shinohara, Kaori Adachi, Masayuki Sasaki, Eiji Nanba, Yoshihiro Maegeki:
    • Journal Title

      Brain and Development

      Volume: 39 Issue: 1 Pages: 67-71

    • DOI

      10.1016/j.braindev.2016.07.004

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 中国人特異的アレルの検索:それは存在するのか.2017

    • Author(s)
      松末 綾、梅津和夫、飯野 守男、湯浅 勲:
    • Journal Title

      DNA多型

      Volume: 25

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Genotyping of the c.1423C>T (p.P475S) polymorphism in the ADAMTS13 gene by APLP and HRM assays: Northeastern Asian origin of the mutant.2016

    • Author(s)
      Mayumi Nakagawa, Aya Matsusue, Kazuo Umetsu, Morio Iino, Takaki Ishikawa, Isao Yuasa:
    • Journal Title

      Legal Medicine

      Volume: 21 Pages: 1-4

    • DOI

      10.1016/j.legalmed.2016.04.010

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] The art of traditional native PAGE: the APLP 48-ID assay for human identification.2016

    • Author(s)
      Kazuo Umetsu, Isao Yuasa, Masaki Hashiyada, et al.
    • Journal Title

      Legal Medicine

      Volume: 19 Pages: 28-31

    • DOI

      10.1016/j.legalmed.2015.12.006

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The global distribution of the p.R1193Q polymorphism in the SCN5A gene.2016

    • Author(s)
      Aya Matsusue, Isao Yuasa, Kazuo Umetsu, et al.
    • Journal Title

      Legal Medicine

      Volume: 19 Pages: 72-76

    • DOI

      10.1016/j.legalmed.2015.07.010

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 日本人特異的アレルによる日本人の証明:JapanesePlexの試み2016

    • Author(s)
      湯浅 勲、山本 敏充、松末 綾、赤根 敦
    • Journal Title

      DNA多型

      Volume: 24

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] High Resolution Melting(HRM)法によるADAMTS13遺伝子c.C1423T(p.P475S)多型の解析2016

    • Author(s)
      中川 真由美、湯浅 勲
    • Journal Title

      DNA多型

      Volume: 24

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Non specific drug distribution in an autopsy case report of fatal caffeine intoxication.2015

    • Author(s)
      Takaki Ishikawa, Isao Yuasa, Minoru Endoh
    • Journal Title

      Legal Medicine

      Volume: 17 Issue: 6 Pages: 535-538

    • DOI

      10.1016/j.legalmed.2015.11.002

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Investigation of Japanese-specific alleles: Most are of Jomon lineage2015

    • Author(s)
      Yuasa I, Umetsu K, Adachi N, Matsusue A, Nakayashiki N, Fujihara J, Akane A, Harihara S, Jin F, Ishikawa T
    • Journal Title

      Leg Med (Tokyo)

      Volume: 17 Issue: 1 Pages: 52-55

    • DOI

      10.1016/j.legalmed.2014.08.006

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mutations in COG2 encoding a subunit of the conserved oligomeric golgi complex cause a congenital disorder of glycosylation2015

    • Author(s)
      17.Kodera H, Ando N, Yuasa I, Wada Y, Tsurusaki Y, Nakashima M, Miyake N, Saitoh S, Matsumoto N, Saitsu H
    • Journal Title

      Clin Genet

      Volume: 87 Issue: 5 Pages: 455-460

    • DOI

      10.1111/cge.12417

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] 日本人特異的遺伝子からみた日本人らしさ:琉球人が和人より日本人らしい2015

    • Author(s)
      湯浅 勲、遠藤 実、石川 隆紀、他
    • Journal Title

      DNA多型

      Volume: 23

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] 中国人特異的アレルの検出2016

    • Author(s)
      松末 綾、梅津和夫、飯野守男、湯浅 勲:
    • Organizer
      第25回日本DNA多型学会学術集会
    • Place of Presentation
      東京大学大気海洋研究所(千葉県柏市)
    • Year and Date
      2016-11-30
    • Related Report
      2016 Annual Research Report
  • [Presentation] 日本人特異的アレルによる日本人の証明:JapanesePlexの試み2015

    • Author(s)
      湯浅 勲、山本 敏充、松末 綾、赤根 敦
    • Organizer
      第24回日本DNA多型学会学術集会
    • Place of Presentation
      岡山大学創立五十周年記念館(岡山市)
    • Year and Date
      2015-11-19
    • Related Report
      2015 Research-status Report
  • [Presentation] High Resolution Melting (HRM)法によるADAMTS13遺伝子c.C1423T(p.P475S)多型の解析2015

    • Author(s)
      中川 真由美、湯浅 勲
    • Organizer
      第24回日本DNA多型学会学術集会
    • Place of Presentation
      岡山大学創立五十周年記念館(岡山市)
    • Year and Date
      2015-11-19
    • Related Report
      2015 Research-status Report
  • [Presentation] ADAMTS13遺伝子のp.P475S多型の地理的分布2015

    • Author(s)
      湯浅 勲、石川 隆紀、松末 綾、中屋敷 徳、西向 弘明
    • Organizer
      第99次日本法医学会学術全国集会
    • Place of Presentation
      高知市文化プラザかるぽーと(高知市)
    • Year and Date
      2015-06-08
    • Related Report
      2015 Research-status Report
  • [Presentation] 法医剖検例における膵臓被膜下・間質内出血の意義についてー予備的検討―2015

    • Author(s)
      石川隆紀、遠藤 実、湯浅 勲
    • Organizer
      第99次日本法医学会学術全国集会
    • Place of Presentation
      高知市文化プラザかるぽーと(高知市)
    • Year and Date
      2015-06-08
    • Related Report
      2015 Research-status Report
  • [Presentation] 日本人特異的遺伝子からみた日本人らしさ2014

    • Author(s)
      湯浅 勲、石川隆紀、梅津和夫、他
    • Organizer
      第23回日本DNA多型学会学術集会
    • Place of Presentation
      愛知県産業労働センターウインクあいち(愛知県名古屋市)
    • Year and Date
      2014-11-26 – 2014-11-28
    • Related Report
      2014 Research-status Report
  • [Presentation] A hypervariable short tandem repeat in intron 7 of the human complement factor I in two Yunnan Chinese populations.2014

    • Author(s)
      Isao Yuasa, Takaki Ishikawa, Kazuo Umetsu, et al.
    • Organizer
      The 9th International Symposium on Advances in Legal Medicine (ISALM)
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-06-16 – 2014-06-20
    • Related Report
      2014 Research-status Report
  • [Presentation] The frequencies of R1193Q polymorphism in the SCN5A gene in the Asian, German and African populations.2014

    • Author(s)
      Aya Matsusue1, Isao Yuasa2, Kazuo Umetsu, et al.
    • Organizer
      The 9th International Symposium on Advances in Legal Medicine (ISALM)
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-06-16 – 2014-06-20
    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi