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Creation of the criterion of the cause of death and the fire cause for fire victims, using the quantitative databases

Research Project

Project/Area Number 26460881
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Legal medicine
Research InstitutionKyushu University

Principal Investigator

Kudo Keiko  九州大学, 医学研究院, 講師 (10186405)

Co-Investigator(Kenkyū-buntansha) 臼元 洋介  横浜市立大学, 医学部, 講師 (50596822)
辻 彰子  九州大学, 医学研究院, 助教 (10171993)
池田 典昭  九州大学, 医学研究院, 教授 (60176097)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords焼死体 / 薬毒物スクリーニング / NAGINATA / GC/MS / LC-MS/MS / シアン / アジ化物 / GC-MS / NAGINATAスクリーニング / 焼死体鑑定 / GC/MSスクリーニング / 揮発性炭化水素 / LC/MS/MSスクリーニング
Outline of Final Research Achievements

We have developed a new NAGINATA-GC/MS screening method that can easily estimate the blood concentrations of volatile hydrocarbons absorbed by combustion of house building materials, gasoline or kerosene. We also developed a reliable and simple determination method of cyanide, thiocyanate and azide in human whole blood, and created the NAGINATA-GC/MS database which can estimate the concentration of the compounds without possessing dangerous poisons as standards. Furthermore, we made a quantitative database of 161 kinds of drugs including hypnotics which are often used in crime purposes, using LC-MS/MS. The databases which we developed have already been used in many forensic laboratories and emergency hospitals, and gives good results for judging the cause of death and the fire cause of the charred body.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (22 results)

All 2017 2016 2015 2014 Other

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 1 results) Presentation (14 results) (of which Int'l Joint Research: 6 results) Remarks (2 results)

  • [Journal Article] A case of acute lidocaine intoxication due to tumescent liposuction2017

    • Author(s)
      Usumoto Y, Kudo K, Sameshima N, Tsuji A, Ikeda N
    • Journal Title

      Acta Crim Japon

      Volume: 83 Pages: 9-14

    • NAID

      40021117757

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of mRNA in the frontal cortex and hypothalamus in a rat model of acute carbon dioxide poisoning2016

    • Author(s)
      Kazuo Sato, Akiko Tsuji, Yosuke Usumoto, Keiko Kudo, Takeshi Yokoyama and Noriaki Ikeda
    • Journal Title

      Legal Medicine

      Volume: 19 Pages: 101-106

    • DOI

      10.1016/j.legalmed.2015.07.014

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 妊婦飛び降りによる胎児脳挫傷の1剖検例2016

    • Author(s)
      上山達也、佐藤和雄、奥村美紀、鮫島直美、工藤恵子、辻 彰子、池田典昭
    • Journal Title

      法医学の実際と研究

      Volume: 59 Pages: 15-20

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A fatal case of poisoning related to new cathinone designer drugs, 4-methoxy PV8, PV9, and 4-methoxy PV9, and a dissociative agent, diphenidine.2015

    • Author(s)
      Kudo K, Usumoto Y, Kikura-Hanajiri R, Sameshima N, Tsuji A, Ikeda N.
    • Journal Title

      Leg Med (Tokyo)

      Volume: 17 Pages: 421-426

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Anomalous origin of the right coronary artery from the left coronary sinus with an intramural course: comparison between sudden-death and non-sudden-death cases.2015

    • Author(s)
      Hata Y, Kinoshita K, Kudo K, Ikeda N, Nishida N.
    • Journal Title

      Cardiovasc Pathol.

      Volume: 24 Pages: 154-159

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] ゾルピデムにより異常行動をとったと考えられる1剖検例2015

    • Author(s)
      臼元洋介、工藤恵子、鮫島直美、佐藤和雄、辻 彰子、池田典昭
    • Journal Title

      福岡医学雑誌

      Volume: 106 Pages: 202-205

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] Reliable determination of cyanide, thiocyanate, and azide in whole blood by GC-MS and its application in NAGINATA-GC-MS screening2017

    • Author(s)
      Kudo K, Usumoto Y, Sameshima N, Okumura M, Tsuji A, Ikeda N
    • Organizer
      2017 SOFT-TIAFT joint annual meeting
    • Place of Presentation
      Boca Raton (USA)
    • Year and Date
      2017-09-09
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Strategies for multiple-target screening using LC-MS/MS with merged spectrum database for forensic toxicology2017

    • Author(s)
      Minohata T, Kudo K, Shima N, Katagi M, Zaitsu K, Tsuchihashi H, Ishii A, Ikeda N
    • Organizer
      2017 SOFT-TIAFT joint annual meeting
    • Place of Presentation
      Boca Raton (USA)
    • Year and Date
      2017-09-09
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A novel target and non-target drug screening using an in silico approach2017

    • Author(s)
      Saka K, Nakazono Y, Kudo K, Minohata T, Kaneshiro M, Hirano I, Furuta K, Fujii Y, Makino Y, Ikeda N, Iwase H
    • Organizer
      2017 SOFT-TIAFT joint annual meeting
    • Place of Presentation
      Boca Raton (USA)
    • Year and Date
      2017-09-09
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] GC-MSによる全血中シアン化物,チオシアン酸塩およびアジ化物の定量方法の改良とNAGINATAスクリーニングへの応用2017

    • Author(s)
      工藤恵子,臼元洋介,鮫島直美,奥村美紀,辻 彰子,池田典昭
    • Organizer
      日本法中毒学会第36年会
    • Place of Presentation
      東京
    • Year and Date
      2017-07-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] GC-MSによる全血中シアン化物,チオシアン酸塩およびアジ化物の定量法の再検討2017

    • Author(s)
      工藤恵子,鮫島直美,奥村美紀,辻 彰子,池田典昭
    • Organizer
      第101次日本法医学会学術全国集会
    • Place of Presentation
      岐阜
    • Year and Date
      2017-06-07
    • Related Report
      2016 Annual Research Report
  • [Presentation] Rapid forensic screening of 161 drugs by ultra-high speed LC/MS/MS with synchronized survey scanning.2015

    • Author(s)
      Minohata T, Kudo K, Shima N, Katagi M, Usui K, Tsuchihashi H, Ikeda N.
    • Organizer
      MSACL 2015 EU
    • Place of Presentation
      Salzburg, Austraia
    • Year and Date
      2015-09-08
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Rapid screening method covers common 161 forensic drugs by ultra-high speed LC/MS/MS with synchronized survey scanning.2015

    • Author(s)
      Minohata T, Kudo K, Shima N, Katagi M, Usui K, Tsuchihashi H, Ikeda N.
    • Organizer
      53rd TIAFT meeting 2015
    • Place of Presentation
      Florence, Italy
    • Year and Date
      2015-08-30
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 危険ドラッグによる中毒死事例における、血液および尿中4-methoxy PV8, PV9, 4-methoxy PV9, diphenidineの同時分析.2015

    • Author(s)
      工藤恵子,臼元洋介, 花尻(木倉)瑠理, 辻 彰子, 池田典昭.
    • Organizer
      日本法中毒学会第34年会.
    • Place of Presentation
      福岡
    • Year and Date
      2015-06-26
    • Related Report
      2015 Research-status Report
  • [Presentation] MRMトリガー自動MS/MS機能を用いた法薬毒物161成分の一斉分析法の開発.2015

    • Author(s)
      箕畑俊和, 工藤恵子,志摩典明, 片木宗弘, 臼井聖尊, 土橋 均, 池田典昭
    • Organizer
      日本法中毒学会第34年会
    • Place of Presentation
      福岡
    • Year and Date
      2015-06-26
    • Related Report
      2015 Research-status Report
  • [Presentation] 睡眠薬およびアルコールの影響下での危険ドラッグによる中毒死の一例.2015

    • Author(s)
      工藤恵子,臼元洋介, 花尻(木倉)瑠理, 鮫島直美, 奥村美紀, 辻 彰子, 池田典昭.
    • Organizer
      第99次日本法医学会学術全国集会.
    • Place of Presentation
      高知
    • Year and Date
      2015-06-10
    • Related Report
      2015 Research-status Report
  • [Presentation] 高濃度のトルエンが検出された腐敗の進行した1剖検例2015

    • Author(s)
      臼元洋介、鮫島直美、工藤恵子、奥村美紀、辻彰子、池田典昭
    • Organizer
      第3回法医中毒研究会勉強会
    • Place of Presentation
      高知
    • Year and Date
      2015-06-10
    • Related Report
      2014 Research-status Report
  • [Presentation] Rapid Screening method covers common 161 forensic drugs by ultra-high speed LC/MS/MS with synchronized survey scanning.2015

    • Author(s)
      Minohata T, Kudo K, Shima N, Katagi M, Usui K, Tsuchihashi H, Suzuki K, Ikeda N.
    • Organizer
      63rd ASMS Conference on Mass Spectrometry and Allied Topics.
    • Place of Presentation
      St. Louis, Missouri, USA
    • Year and Date
      2015-05-31
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 定量的データベースを用いた焼死体の死因・火災原因判断基準の作成(第1報)2014

    • Author(s)
      工藤恵子、臼元洋介、鮫島直美、辻 彰子、池田典昭
    • Organizer
      第61回日本法医学会学術近畿地方集会
    • Place of Presentation
      西の宮市
    • Year and Date
      2014-11-08
    • Related Report
      2014 Research-status Report
  • [Presentation] Rapid and simultaneous extraction of acidic and basic drugs using modified QuEChERS method and protein-lipid removal filter cartridge2014

    • Author(s)
      Kudo K, Usumoto Y, Usui K, Hayashida H, Kurisaki E, Saka K, Tsuji A, Ikeda N
    • Organizer
      9th International Symposium on Advances in Legal Medicine (ISALM)
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2014-06-16 – 2014-06-20
    • Related Report
      2014 Research-status Report
  • [Remarks] 九州大学研究者情報

    • URL

      http://hyoka.ofc.kyushu-u.ac.jp/search/details/K000859/index.html

    • Related Report
      2015 Research-status Report
  • [Remarks] 九州大学大学院医学研究院法医学分野ホームページ

    • URL

      http://www.med.kyushu-u.ac.jp/forensic/index.html

    • Related Report
      2015 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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