| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
|---|
| Outline of Final Research Achievements |
Different enteral nutrition of three kinds of nutrients were randomly applied to 18 elderly diabetic patients who made PEG (Percutaneous Endoscopic Gastrostomy) and the５elderly nondiabetic subjects. Continuous blood glucose measurement （CGM）was carried out every 5 hours for 72 hours, and the time series data were analyzed by non-liner time series analysis was performed to evaluate the complexity of blood glucose fluctuation and examined whether it is predictable or not.
The complexity was significantly decreased in DM group (1.379 ± 0.069 vs. 1.484 ± 0.073, P = 0.012) by using Detrended Fluctuation Analysis (DFA) analysis. And same results showed by using Fast Fourier Transform (1.734± 0.105 vs. 2.617 ± 0.329, P <0.001). In addition, the decrease DFA was significantly negative correlated with insulin secretion (R2=0.33, P<0.01). Thus, blood glucose fluctuation could predict insulin secretion as an explanatory variable.
|
