Problem solving of the coronary bifurcation stenting using 3-dimensional optical coherence tomography and developing the dedicated bioresorbable scaffold
Project/Area Number |
26461071
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Cardiovascular medicine
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Research Institution | Yamaguchi University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
南 和幸 山口大学, 創成科学研究科, 教授 (00229759)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2014: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
|
Keywords | 虚血性心疾患 / 冠動脈ステント / 光干渉断層法 / 動脈硬化 / 画像診断 / ポリマー |
Outline of Final Research Achievements |
We investigated the serial change of the side branch ostium jailed by drug eluting stent in the coronary artery bifurcation lesion by the three-dimensional optical coherence tomography. The response of the remote phase is different depending on the complexity of the stent covering configuration. The side branch ostial area decreased at the remote period when the stent covering configuration was complicated. In the case of side branch dilatation, when the number of remaining struts was large, the ostial areas often decreased in the remote period. The frequency of the remaining strut after side branch dilatation was higher when the longitudinal stent link was present at the carina. We developed a dedicated bioresorbable scaffold for the bifurcation lesion and evaluate them in the simulated phantom vessel. It was observed the cutting of the longitudinal link of the stent and that the side branch ostium was opened widely.
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Report
(4 results)
Research Products
(22 results)
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[Journal Article] Serial changes in the three-dimensional aspect of the side-branch ostium jailed by a drug-eluting stent assessed by optical coherence tomography.2017
Author(s)
Nakamura T, Okamura T, Fujimura T, Yamada J, Nao T, Tateishi H, Maeda T, Oda T, Shiraishi K, Nakashima T, Nishimura S, Miura T, Matsuzaki M, Yano M.
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Journal Title
Int J Cardiovasc Imaging
Volume: 33
Issue: 6
Pages: 797-806
DOI
Related Report
Peer Reviewed
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[Journal Article] Differences of side branch jailing between left main-left anterior descending artery stenting and left main-left circumflex artery stenting with Nobori biolimus-eluting stent.2016
Author(s)
Nakao F, Okamura T, Suetomi T, Yamada J, Nakamura T, Ueda T, Oda T, Kanemoto M, Ikeda Y, Fujii T, Yano M.
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Journal Title
Heart Vessels
Volume: 31
Issue: 12
Pages: 1895-1903
DOI
Related Report
Peer Reviewed
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[Journal Article] New quantitative method to diagnose coronary in-stent restenosis by 64-multislice computed tomography2015
Author(s)
Yoshimura M, Nao T, Miura T, Okada M, Nakashima Y, Fujimura T, Okamura T, Yamada J, Matsunaga N, Matsuzaki M, Yano M.
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Journal Title
J Cardiol
Volume: 65
Issue: 1
Pages: 57-62
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Impact of angiographic peri-stent contrast staining (PSS) on late adverse events after sirolimus-eluting stent implantation: an observation from the multicenter j-Cypher registry PSS substudy.2014
Author(s)
Imai M, Kimura T, Morimoto T, Saito N, Shiomi H, Kawaguchi R, Kan H, Mukawa H, Fujita H, Ishise T, Hayashi F, Nagao K, Take S, Taniguchi H, Sakamoto H, Yamane T, Shirota K, Tamekiyo H, Okamura T, Kishi K, Miyazaki S, Yamamoto S, Yamaji K, Kawasaki T, Taguchi E, Nakajima H, Kosedo I, Tada T, Kadota K, Mitsudo K.
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Journal Title
Cardiovasc Interv Ther.
Volume: 29
Issue: 3
Pages: 226-36
DOI
NAID
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] 3D optical coherence tomography: new insights into the process of optimal rewiring of side branches during bifurcational stenting2014
Author(s)
Okamura T, Onuma Y, Yamada J, Iqbal J, Tateishi H, Nao T, Oda T, Maeda T, Nakamura T, Miura T, Yano M, Serruys PW.
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Journal Title
EuroIntervention
Volume: 10
Issue: 8
Pages: 907-15
DOI
Related Report
Peer Reviewed
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[Journal Article] Serial three-dimensional optical coherence tomography assessment of strut coverage and intraluminal structures after drug-eluting stent implantation2014
Author(s)
Maeda T, Okamura T, Yamada J, Nao T, Tateishi H, Yoshimura M, Oda T, Shiraishi K, Nakashima T, Nakamura T, Miura T, Yano M
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Journal Title
Cardiovasc Interv Ther
Volume: 29(1)
Issue: 1
Pages: 31-9
DOI
Related Report
Peer Reviewed
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[Journal Article] Dual-source computed tomography coronary angiography in patients with high heart rate.2013
Author(s)
Fujimura T, Miura T, Nao T, Yoshimura M, Nakashima Y, Okada M, Okamura T, Yamada J, Ohshita C, Wada Y, Matsunaga N, Matsuzaki M, Yano M.
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Journal Title
Heart Vessels
Volume: 29
Issue: 4
Pages: 443-8
DOI
Related Report
Peer Reviewed
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[Presentation] Serial change of side branch ostial areas after single crossover stenting with KBD assessed by 3D OCT2016
Author(s)
Tatsuhiro Fujimura, Takayuki Okamura, Jutaro Yamada, Tetsuro Oda, Mamoru Mochizuki, Yousuke Miyazaki, Takeshi Suetomi, Akihiro Hino, Shigehiko Nishimura, Takashi Nishimura, Masafumi Yano
Organizer
第64回日本心臓病学会学術集会
Place of Presentation
東京国際フォーラム(東京都千代田区)
Year and Date
2016-09-24
Related Report
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[Presentation] 左主幹部分岐部病変における single stent治療とtwo stent治療の治療成績比較 ―分岐角度を踏まえた検討-2015
Author(s)
宮崎 要介, 岡村 誉之, 山田 寿太郎, 西村 傑, 西村 滋彦, 日野 昭宏, 末冨 建, 藤村 達大, 望月 守, 小田 哲朗, 矢野 雅文
Organizer
日本心臓病学会学術集会
Place of Presentation
横浜(パシフィコ横浜)
Year and Date
2015-09-18
Related Report
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[Presentation] Impact of the jailing configuration after bifurcational stenting on the side branch ostial stenosis at follow up2014
Author(s)
Takeshi Nakamura, Takayuki Okamura, Jutaro Yamada, Hiroki Tateishi, Takao Maeda, Tomoko Nao, Tetsuro Oda, Mamoru Mochizuki, Kozo Shiraishi, Masafumi Yano
Organizer
European Society of Cardiology, Congress 2014
Place of Presentation
バルセロナ、スペイン
Year and Date
2014-08-30 – 2014-09-03
Related Report
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