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CFAE ablation in persistent AF

Research Project

Project/Area Number 26461077
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Cardiovascular medicine
Research InstitutionKagoshima University

Principal Investigator

Oketani Naoya  鹿児島大学, 医歯学総合研究科, 客員研究員 (70598010)

Co-Investigator(Kenkyū-buntansha) 宮田 昌明  鹿児島大学, 医歯学総合研究科, 客員研究員 (00347113)
大石 充  鹿児島大学, 医歯学域医学系, 教授 (50335345)
Project Period (FY) 2014-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords心房細動 / カテーテルアブレーション
Outline of Final Research Achievements

First, we studied the perioperative use of DOACs. In comparison with rivaroxaban and apixaban, occurrence of perioperative asymptomatic stoke and cardiac tamponade were not different between the two groups (J Cardiol. 2017, ESC 2015, APHRS 2015, JCS 2016). In comparison with rivaroxaban and edoxaban, occurrence of perioperative asymptomatic stoke and cardiac tamponade were not different between the two groups, but low dose in both groups had more asymptomatic stoke (APHRS 2018, JCS 2019). Second, next is the main topic in our study for this grant. CFAE ablation was quite good for persistent AF and additional PVI did not have additional effects for the outcome of the ablation for persistent AF. We reported that in Heart Rhythm 2016, ESC 2015. Third, we reported about the diastolic function in AF in JCS 2016, atrial conduction time in AF in JHRS 2016, volume overload in AF ablation in JHRS 2017. Finally, combined with spatiotemporal electrogram dispersion in the symposium of APHRS2018.

Academic Significance and Societal Importance of the Research Achievements

心房細動のCFAEアブレーションに精通している当院でしか行えない研究で、学術的意義も高く、他施設への影響も大きいために社会的意義も高いと考えられる。

Report

(6 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (23 results)

All 2019 2018 2017 2016 2015 2014 Other

All Int'l Joint Research (8 results) Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Acknowledgement Compliant: 1 results) Presentation (12 results) (of which Int'l Joint Research: 5 results,  Invited: 1 results) Book (1 results)

  • [Int'l Joint Research] Zwolle(オランダ)

    • Related Report
      2017 Research-status Report
  • [Int'l Joint Research] Pacific Rim(米国)

    • Related Report
      2017 Research-status Report
  • [Int'l Joint Research] Saint Joseph/Pasteur(フランス)

    • Related Report
      2017 Research-status Report
  • [Int'l Joint Research] Bumrungrad International Hospital(タイ)

    • Related Report
      2017 Research-status Report
  • [Int'l Joint Research] Zwolle(オランダ)

    • Related Report
      2016 Research-status Report
  • [Int'l Joint Research] Pacific Rim(米国)

    • Related Report
      2016 Research-status Report
  • [Int'l Joint Research] Saint Joseph/Pasteur(フランス)

    • Related Report
      2016 Research-status Report
  • [Int'l Joint Research] Bumrungrad Internatinal Hospital(タイ)

    • Related Report
      2016 Research-status Report
  • [Journal Article] Evaluation of safety and efficacy of periprocedural use of rivaroxaban and apixaban in catheter ablation for atrial fibrillation.2017

    • Author(s)
      Yoshimura A, Iriki Y, Ichiki H, Oketani N, Okui H, Maenosono R, Namino F, Miyata M, Ohishi M.
    • Journal Title

      J Cardiol. 2017

      Volume: 69 Issue: 1 Pages: 228-235

    • DOI

      10.1016/j.jjcc.2016.03.014

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Ablation of complex fractionated electrograms is useful for catheter ablation of persistent atrial fibrillation: Protagonist point of view.2016

    • Author(s)
      Oketani N, Seitz J, Salazar M, Pisapia A, Kalifa J, Smit JJ, Nademanee K.
    • Journal Title

      Heart Rhythm.

      Volume: 13 Issue: 10 Pages: 2098-2100

    • DOI

      10.1016/j.hrthm.2016.06.036

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Incidence of Asymptomatic Stroke or Hemopericardium in Catheter Ablation for Atrial Fibrillation Compared with Uninterrapted use of Edoxaban, Rivaroxaban, or Warfarin2019

    • Author(s)
      Issei Yoshimoto
    • Organizer
      日本循環器学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Spatiotemporal Electrogram Dispersion Combined with CFAE Ablation2018

    • Author(s)
      Naoya Oketani
    • Organizer
      アジア太平洋不整脈学会
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Incidence of Asymptomatic Stroke or Hemopericardium in Catheter Ablation for Atrial Fibrillation Compared with Uninterrapted use of Edoxaban, Rivaroxaban, or Warfarin2018

    • Author(s)
      Issei Yoshimoto
    • Organizer
      アジア太平洋不整脈学会
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 心臓カテーテルアブレーション時の点滴過負荷による心不全発症の有無に関与する因子について2017

    • Author(s)
      佐藤 妙子
    • Organizer
      日本不整脈学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 心房細動に対するComplex fractionated atrial electrogram アブレーション前後の全心房伝導時間PA-TDI durationと心房細動再発との関連2016

    • Author(s)
      前之園 隆一、桶谷 直也、水上 尚子、入來 泰久、奥井 英樹、吉村 あきの、市來 仁志、波野 史典、松下 昌風、茶圓 秀人、堀添 善尚、高崎 州亜、湯浅 敏則、木佐貫 彰、宮田 昌明、大石 充、橋口 照人
    • Organizer
      日本不整脈心電学会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-07-14
    • Related Report
      2016 Research-status Report
  • [Presentation] Evaluation of Safety and Efficacy of Periprocedural Use of Rivaroxaban and Apixaban in Atrial Fibrillation Ablation2016

    • Author(s)
      Yoshimura A, Iriki Y, Ichiki H, Oketani N, Okui H, Maenosono R, Ninomiya Y, Miyata M, Ohishi M.
    • Organizer
      日本循環器学会
    • Place of Presentation
      せんだい青葉山交流広場(宮城県仙台市)
    • Year and Date
      2016-03-18
    • Related Report
      2015 Research-status Report
  • [Presentation] Evaluation of Left Ventricular Diastolic Function in Patients with Atrial Fibrillation2016

    • Author(s)
      Akino Yoshimura、Naoya Oketani、Yasuhisa Iriki、Hideki Okui、Ryuichi Maenosono、Fuminori Namino、Toshinori Yuasa、Masaaki Miyata、Mitsuru Ohishi
    • Organizer
      日本循環器学会
    • Place of Presentation
      せんだい青葉山交流広場(宮城県仙台市)
    • Year and Date
      2016-03-18
    • Related Report
      2015 Research-status Report
  • [Presentation] Comparison of substrate ablation with or without anatomical ablation for atrial fibrillation.2015

    • Author(s)
      Iriki Y, Oketani N, Yoshimura A, Ichiki H, Okui H, Maenosono R, Namino F, Ohishi M.
    • Organizer
      アジア・太平洋不整脈学会
    • Place of Presentation
      オーストラリア メルボルン
    • Year and Date
      2015-11-19
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Comparison of substrate ablation with or without anatomical ablation for atrial fibrillation: Does pulmonary vein isolation prior to substrate ablation improve the outcome?2015

    • Author(s)
      Yoshimura A, Ichiki H, Oketani N, Iriki Y, Okui H, Maenosono R, Ninomiya Y, Miyata M, Ohishi M.
    • Organizer
      ヨーロッパ心臓病学会
    • Place of Presentation
      スペイン バルセロナ
    • Year and Date
      2015-08-29
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Evaluation of Safety and Efficacy of Periprocedural Use of Rivaroxaban and Apixaban in Catheter Ablation for Atrial Fibrillation.2015

    • Author(s)
      Iriki Y, Ichiki H, Oketani N, Yoshimura A, Okui H, Maenosono R, Ninomiya Y, Miyata M, Ohishi M.
    • Organizer
      ヨーロッパ心臓病学会
    • Place of Presentation
      スペイン バルセロナ
    • Year and Date
      2015-08-29
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Atrial Fibrillation Termination Caused by Pulmonary Vein Isolation Prior to Complex Fractionated Atrial Electrograms Guided Ablation.2014

    • Author(s)
      吉村 あきの
    • Organizer
      ヨーロッパ心臓病学会
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2014-09-02
    • Related Report
      2014 Research-status Report
  • [Presentation] Substrate Ablation of Atrial Fibrillation Guided by Complex Fractionated Atrial Electrograms: Repeated Ablations are Suitable in Patients with History of any Types of Ablations for Atrial Fibrillation.2014

    • Author(s)
      桶谷 直也
    • Organizer
      日本不整脈学会
    • Place of Presentation
      東京(ザ・プリンスパークタワー東京)
    • Year and Date
      2014-07-23
    • Related Report
      2014 Research-status Report
  • [Book] Heart View2014

    • Author(s)
      桶谷 直也
    • Total Pages
      100
    • Publisher
      メジカルビュー社
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2022-02-21  

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