| Project/Area Number |
26461079
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cardiovascular medicine
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| Research Institution | Yokohama City University |
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Principal Investigator |
Hibi Kiyoshi 横浜市立大学, 附属市民総合医療センター, 准教授 (20347339)
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| Co-Investigator(Kenkyū-buntansha) |
松下 絢介 横浜市立大学, 附属市民総合医療センター, 常勤診療医 (70727825)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
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| Keywords | iFR / FFR / IVUS / OFDI |
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| Outline of Final Research Achievements |
Eighty lesions in 72 patients who underwent elective angiography and had intermediate lesions were enrolled. All lesions were assessed by instantaneous wave-flow ratio (iFR), fractional flow reserve (FFR), intravascular ultrasound (IVUS), optical frequency domain imaging (OFDI). iFR and FFR demonstrated moderate overall linear correlation with r value of 0.63 (p<0.001).iFR correlated significantly with both IVUS-derived minimum lumen area (MLA) (r=0.375, p=0.003) and OFDI-derived MLA (r=0.357, p=0.005). FFR also correlated significantly with both IVUS-derived MLA (r=0.472, p<0.001) and OFDI-derived MLA (r=0.445, p<0.001).
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