| Project/Area Number |
26461204
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Nippon Medical School |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
寺崎 泰弘 日本医科大学, 医学部, 准教授 (50332870)
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| Co-Investigator(Renkei-kenkyūsha) |
MIYAKE KOUICHI 日本医科大学, 医学部, 准教授 (90267211)
NAGASAKA SHINYA 日本医科大学, 医学部, 助教 (00573239)
TERASAKI MIKA 日本医科大学, 医学部, 助教 (50372785)
SEIKE MASAHIRO 日本医科大学, 医学部, 准教授 (30366687)
ISHIKAWA ARIMI 日本医科大学, 医学部, 研究員 (40598992)
KUWAHARA NAOMI 日本医科大学, 医学部, 研究員 (00599011)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 気管支肺胞洗浄液 / マイクロRNA / エクソソーム / II型肺胞上皮 / 間質性肺炎 / miRNA / エクソゾーム / microRNA |
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| Outline of Final Research Achievements |
We performed micro RNA analysis of serum, bronchoalveolar lavage, and lung tissue of bleomycin-induced pneumonitis in mice. Particularly, We analyzed exosomal franction and others fraction of bronchoalveolar lavage.In fibrotic stage,the elevation of miR-150 were confirmed.
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