| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Outline of Final Research Achievements |
Inherited metabolic disorders of trace elements are rare, but difficult to diagnose clinically as well as pathologically. We tried to incorporate synchrotron-generated brilliant X-ray to pathological examination and successfully detected trace elements in tissue sections; such as copper, iron and zinc. We also achieved to simultaneously create two-dimensional elemental maps. These elemental disorders, that have been impossible to capture pathological study, are now readily diagnosing by synchrotron X-ray fluorescence analysis. Now, we open the door to elemental pathology. The diagnosis and pathogenesis of abnormality in trace elements can be analyzed with a new aspect.
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