|Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|Outline of Final Research Achievements
Though we induced proteinuria the podocyte-specific conditional knockout mice of this transport protein with LPS, we could not find strong tendency of the degree of albuminuria in knockout mice compared with control. We created the tamoxifen-inducible knockout mice of this transport protein. After tamoxifen administration, poor weight gain and atypical glands in intestine was found in these knockout mice.