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Prediction of neonatal chronic lung disease by serum syndecan-4

Research Project

Project/Area Number 26461642
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Embryonic/Neonatal medicine
Research InstitutionKeio University

Principal Investigator

Ikeda Kazushige  慶應義塾大学, 医学部, 講師 (00193194)

Co-Investigator(Kenkyū-buntansha) 松崎 陽平  慶應義塾大学, 医学部(信濃町), 助教 (60327583)
谷野 功典  福島県立医科大学, 医学部, 准教授 (10443863)
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordssyndecan-4 / 慢性肺疾患 / 絨毛膜羊膜炎 / 臍帯血 / 胎児血
Outline of Final Research Achievements

We made a hypothesis that syndecan-4 elevated in chronic lung disease infant after chorioanmionatis and that the difference in expression of syndecan-4 in early time after delivery could reflect degree of chronic lung disease in preterm infants.
First, we measured syndecan-4 in term infants for reference value. We tried the measurement of syndecan-4 in preterm infants, however,umbilical cord blood or residual serum for this study were too insufficient to analyze even after one year extension of the research.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (8 results)

All 2016 2015 2014

All Journal Article (2 results) Presentation (6 results)

  • [Journal Article] 早産児と正期産児の血清syndecan-4の比較検討2016

    • Author(s)
      松崎陽平, 池田一成, 谷野功典, 王新涛, 棟方充
    • Journal Title

      分子呼吸器病

      Volume: 20 Pages: 127-131

    • Related Report
      2015 Research-status Report
  • [Journal Article] 新生児一過性多呼吸2016

    • Author(s)
      松崎陽平
    • Journal Title

      周産期医学

      Volume: 46

    • Related Report
      2015 Research-status Report
  • [Presentation] 早産児と満期の早期正期産児の血清syndecan-4の比較検討2015

    • Author(s)
      松崎陽平
    • Organizer
      日本周産期・新生児医学会学術集会
    • Place of Presentation
      ヒルトン福岡シーホーク(福岡県福岡市)
    • Year and Date
      2015-07-10
    • Related Report
      2015 Research-status Report
  • [Presentation] 早産児と満期の早期正期産児の血清syndecan-4の比較検討2015

    • Author(s)
      松崎陽平
    • Organizer
      肺サーファクタント分子病態研究会
    • Place of Presentation
      札幌医科大学講堂(北海道札幌市)
    • Year and Date
      2015-06-06
    • Related Report
      2015 Research-status Report
  • [Presentation] 新生児1か月までの血清syndecan-4の変化2014

    • Author(s)
      松崎陽平、池田一成
    • Organizer
      第59回日本未熟児新生児学会・学術集会
    • Place of Presentation
      ひめぎんホール
    • Year and Date
      2014-11-10 – 2014-11-12
    • Related Report
      2014 Research-status Report
  • [Presentation] 臍帯血と満期新生児早期の血清syndecan-4の比較2014

    • Author(s)
      松崎陽平、池田一成
    • Organizer
      第47回日本小児呼吸器学会
    • Place of Presentation
      秋葉原コンベンションホール
    • Year and Date
      2014-10-24 – 2014-10-25
    • Related Report
      2014 Research-status Report
  • [Presentation] 臍帯血と満期新生児早期の血清syndecan-4の比較2014

    • Author(s)
      松崎陽平、池田一成
    • Organizer
      第27回新生児慢性肺疾患研究会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2014-10-18
    • Related Report
      2014 Research-status Report
  • [Presentation] 満期の新生児早期における血清syndecan-4の基準値の作成2014

    • Author(s)
      松崎陽平、池田一成
    • Organizer
      第50回日本周産期・新生児医学会学術集会
    • Place of Presentation
      シェラトン・グランデ・トーキョーベイ・ホテル
    • Year and Date
      2014-07-13 – 2014-07-15
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2019-03-29  

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